Genome-wide Screen in S. Cerevisiae

Web supplement to
"Gene annotation and drug target discovery in C. albicans with a tagged transposon mutant collection "

Julia Oh, Eula Fung, Ulrich Schlecht, Ronald W. Davis, Guri Giaever, Robert P. St.Onge, Adam Deutschbauer, Corey Nislow

tbd

Supplementary Figures

Figure Title
Figure S1 Multiple genomic libraries are necessary to improve genome coverage.
Figure S2 Scheme and validation for using one tag per strain.
Figure S3 Cross-hybridization of tagged strains to unused tags.
Figure S4 Confirmation of haploinsufficient phenotype with GRACE strains.
Figure S5 Additional complementation tests of C. albicans ORFs.
Figure S6 Additional dose response curves.
Figure S7 Chemical structures of compounds screened in the pooled growth assay.
Figure S8 Distribution of pair-wise compound similarity.

 

 

Inquiries can be addressed to guri.giaever@utoronto.ca OR corey.nislow@utoronto.ca