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YPR104C / FHL1

Section 1: Phenotypes.
Gene-drug relationships for YPR104C
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YPR104C deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

Heterozygous knockout:

Top 10 sensitivity-inducing conditions for FHL1 Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
no drug minimal media 0 70.1654 5.5698e-09
no drug minimal media 0 68.3677 6.3407e-09
no drug minimal media 0 66.9619 3.7306e-10
no drug minimal media 0 59.1999 1.3014e-08
no drug minimal media 0 58.2649 1.409e-08
no drug minimal media 0 57.2652 1.5362e-08
no drug minimal media 0 51.2519 1.851e-09
no drug minimal media 0 25.8341 1.1089e-07
no drug minimal media 0 23.5904 1.9039e-07
caspofungin 10 nM 7.73402 3.2018e-10

More... (click to see all Heterozygous data)

Homozygous knockout:

[No Homozygous results.]

Section 2: Co-fitness interactions.
Gene-gene relationships for YPR104C

Top 10 functional gene interactors with YPR104C. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.

Heterozygous co-fitness interactions

Top 10 interactors with FHL1 by heterozygous co-sensitivity:

Query Interactor Correlation
FHL1 YAR1 0.59015
FHL1 IFH1 0.58684
FHL1 POR1 0.58359
FHL1 PGA3 0.58246
FHL1 TUB4 0.57767
FHL1 ATP11 0.57553
FHL1 MEF1 0.57453
FHL1 POB3 0.57035
FHL1 RAD52 0.57032
FHL1 MGE1 0.5623

More... (click to see all interactions)

Enriched GO terms of interactors

Homozygous co-fitness interactions

[No homozygous results.]

External information about YPR104C

Other databases:

Visit YPR104C in [ SGD | TheBioGrid | BioPixie ]

Previously known GO terms:
Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.

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