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Yeast Fitness
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YPR086W / SUA7



Section 1: Phenotypes.
Gene-drug relationships for YPR086W
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YPR086W deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

.
Heterozygous knockout:

Top 10 sensitivity-inducing conditions for SUA7 Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
wiskostatin 29 uM 6.28326 2.3962e-07
dna protein kinase inhibitor 0 4.30219 7.4395e-05
dyclonine 500 uM 3.73746 0.0014175
cantharidin 250 uM 3.67552 0.033351
fenpropimorph 4.7 uM 3.61947 0.00036013
rapamycin 9 nM 3.45391 0.00078858
alverine citrate 500 uM 3.421 0.037926
dyclonine 500 uM 3.3109 0.003107
itraconazole 8.8 uM 3.20381 0.0012185
dyclonine 500 uM 2.94088 0.0025325

More... (click to see all Heterozygous data)

 
Homozygous knockout:

[No Homozygous results.]




Section 2: Co-fitness interactions.
Gene-gene relationships for YPR086W

Top 10 functional gene interactors with YPR086W. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.



Heterozygous co-fitness interactions

Top 10 interactors with SUA7 by heterozygous co-sensitivity:

Query Interactor Correlation
SUA7 DED1 0.51004
SUA7 GAA1 0.50795
SUA7 TOP3 0.49795
SUA7 YNL018C 0.49669
SUA7 PFS2 0.4858
SUA7 HEM4 0.47537
SUA7 TRS31 0.46606
SUA7 YDR341C 0.46475
SUA7 YDL038C 0.45623
SUA7 KRE5 0.44057

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:
  • None
Component:
  • None
 
Homozygous co-fitness interactions

[No homozygous results.]




External information about YPR086W

Other databases:

Visit YPR086W in [ SGD | TheBioGrid | BioPixie ]


Previously known GO terms:
Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.


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