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Yeast Fitness

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YPL117C / IDI1

Section 1: Phenotypes.
Gene-drug relationships for YPL117C
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YPL117C deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

Heterozygous knockout:

Top 10 sensitivity-inducing conditions for IDI1 Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
cantharidin disodium 100 uM 4.83689 1.5953e-05
cocl2 1250 uM 3.74286 0.00035851
methotrexate 500 uM 3.39859 0.0096403
methotrexate 250 uM 3.33659 0.00083199
5-fluorouracil 38.5 uM 3.11312 0.013229
ID 688028 1.9 uM 2.92181 0.0031677
atorvastatin 125 uM 2.79357 0.0037596
pimethixene maleate 125 uM 2.62817 0.00578
cloxyquin 15.6 uM 2.61329 0.0060037
resveratrol 2000 uM 2.44403 0.010109

More... (click to see all Heterozygous data)

Homozygous knockout:

[No Homozygous results.]

Section 2: Co-fitness interactions.
Gene-gene relationships for YPL117C

Top 10 functional gene interactors with YPL117C. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.

Heterozygous co-fitness interactions

Top 10 interactors with IDI1 by heterozygous co-sensitivity:

Query Interactor Correlation
IDI1 SEN34 0.4885
IDI1 RFC2 0.48319
IDI1 PEP5 0.48304
IDI1 TFC3 0.47909
IDI1 BRL1 0.4783
IDI1 BUD14 0.46594
IDI1 PRP45 0.45803
IDI1 NSE5 0.45663
IDI1 SUI1 0.45211
IDI1 THG1 0.44561

More... (click to see all interactions)

Enriched GO terms of interactors

  • None
  • None
  • None
Homozygous co-fitness interactions

[No homozygous results.]

External information about YPL117C

Other databases:

Visit YPL117C in [ SGD | TheBioGrid | BioPixie ]

Previously known GO terms:
Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.

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