Retrieving results for YOR235W, please wait...

Yeast Fitness
Database

Quick Search

Enter orf / gene / drug:

(e.g. pex22 or lovastatin)  
Advanced search

YOR235W / IRC13



Section 1: Phenotypes.
Gene-drug relationships for YOR235W
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YOR235W deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

.
Heterozygous knockout:

Top 10 sensitivity-inducing conditions for IRC13 Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
dyclonine 500 uM 13.0975 < 1e-12
lovastatin 77.2 uM 10.3641 < 1e-12
nacl 700 mM 8.70848 2.98e-10
dihydromotuporamine C 15 uM 7.07758 2.5001e-08
tomatine 62.5 uM 5.45678 8.8435e-07
dihydromotuporamine C 7.5 uM 5.27801 4.4247e-06
acriflavinium hydrochloride 250 uM 4.14354 7.0691e-05
thiabendazole 500 uM 4.11511 7.7394e-05
tryptanthrin 250 uM 3.77386 0.00032906
fluconazole 130.6 uM 3.54049 0.00045644

More... (click to see all Heterozygous data)

 
Homozygous knockout:

Top 10 sensitivity-inducing conditions for IRC13 Homozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
licl 100 mM 9.1903 1.6109e-08
synthetic complete for BY4743 0 7.75256 0.0081171
synthetic complete for BY4743 0 5.85166 0.013992
norcantharidin 2500 uM 3.35957 0.00096899
wiskostatin 29 uM 3.07983 0.0020415
phosphatase inhibitor 3 uM 2.88639 0.0033628
synthetic complete for BY4743 0 2.57474 0.041077
yp glycerol 0 2.35505 0.020146
chemdiv 218 250 uM 2.28682 0.014278
norcantharidin 2500 uM 2.14711 0.019501

More... (click to see all Homozygous data)





Section 2: Co-fitness interactions.
Gene-gene relationships for YOR235W

Top 10 functional gene interactors with YOR235W. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.



Heterozygous co-fitness interactions

Top 10 interactors with IRC13 by heterozygous co-sensitivity:

Query Interactor Correlation
IRC13 MET7 0.51975
IRC13 DDP1 0.49305
IRC13 ERJ5 0.48099
IRC13 SEC63 0.46934
IRC13 ARG82 0.4632
IRC13 DBP3 0.46006
IRC13 TMA19 0.45577
IRC13 ODC2 0.45291
IRC13 CDH1 0.4501
IRC13 DOC1 0.44894

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:Component:
  • None
 
Homozygous co-fitness interactions

Top 10 interactors with IRC13 by homozygous co-sensitivity:

Query Interactor Correlation
IRC13 RPS28A 0.61337
IRC13 RPS17B 0.59962
IRC13 RPS18B 0.59856
IRC13 RPL2A 0.59855
IRC13 RPS0A 0.59454
IRC13 RPL13A 0.58889
IRC13 YDL063C 0.58836
IRC13 RPS30A 0.58816
IRC13 RPS7B 0.58606
IRC13 FYV12 0.58486

More... (click to see all interactions)

Enriched GO terms of interactors

Process:Function:Component:




External information about YOR235W

Other databases:

Visit YOR235W in [ SGD | TheBioGrid | BioPixie ]


Previously known GO terms:
    Process:
    • None
    Function:
    • None
    Component:
    • None

Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.


Download a plain text version of this page.