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Yeast Fitness
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YOR232W / MGE1



Section 1: Phenotypes.
Gene-drug relationships for YOR232W
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YOR232W deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

.
Heterozygous knockout:

Top 10 sensitivity-inducing conditions for MGE1 Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
tomatine 62.5 uM 9.4984 2.445e-12
methotrexate 125 uM 8.84703 2.0767e-10
cocl2 1250 uM 8.62532 3.7057e-10
no drug minimal media 0 7.93411 0.00025619
dna protein kinase inhibitor 0 7.51953 7.2992e-09
dihydromotuporamine C 15 uM 7.44103 9.0691e-09
no drug minimal media 0 6.65843 0.0005765
nacl 700 mM 6.31501 2.1871e-07
no drug minimal media 0 5.9278 0.00097439
methotrexate 125 uM 5.761 1.0853e-06

More... (click to see all Heterozygous data)

 
Homozygous knockout:

[No Homozygous results.]




Section 2: Co-fitness interactions.
Gene-gene relationships for YOR232W

Top 10 functional gene interactors with YOR232W. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.



Heterozygous co-fitness interactions

Top 10 interactors with MGE1 by heterozygous co-sensitivity:

Query Interactor Correlation
MGE1 SSY1 0.7717
MGE1 YML6 0.75293
MGE1 RIB2 0.73252
MGE1 HEM14 0.73219
MGE1 POR1 0.72836
MGE1 SPT5 0.72524
MGE1 RFA2 0.72229
MGE1 ALF1 0.71721
MGE1 SLA2 0.71673
MGE1 NAB2 0.71327

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:
  • None
Component:
  • None
 
Homozygous co-fitness interactions

[No homozygous results.]




External information about YOR232W

Other databases:

Visit YOR232W in [ SGD | TheBioGrid | BioPixie ]


Previously known GO terms:
Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.


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