Retrieving results for YOL030W, please wait...

Yeast Fitness
Database

Quick Search

Enter orf / gene / drug:

(e.g. pex22 or lovastatin)  
Advanced search

YOL030W / GAS5



Section 1: Phenotypes.
Gene-drug relationships for YOL030W
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YOL030W deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

.
Heterozygous knockout:

Top 10 sensitivity-inducing conditions for GAS5 Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
no drug minimal media 0 51.4222 2.629e-08
no drug minimal media 0 45.7295 4.7215e-08
no drug minimal media 0 33.2733 2.4521e-08
no drug minimal media 0 30.952 3.7759e-08
no drug minimal media 0 21.2551 3.5355e-07
no drug minimal media 0 20.6234 4.2281e-07
no drug minimal media 0 17.8576 5.0545e-06
no drug minimal media 0 17.3181 5.8801e-06
no drug minimal media 0 16.8343 6.761e-06
doxorubicin 62.5 uM 6.96212 4.6664e-09

More... (click to see all Heterozygous data)

 
Homozygous knockout:

Top 10 sensitivity-inducing conditions for GAS5 Homozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
licl 150 mM 8.92212 9.9454e-11
licl 150 mM 8.60845 2.3353e-10
wiskostatin 29 uM 5.65362 1.2141e-06
licl 100 mM 5.49463 1.612e-05
cuso4 12000 uM 5.40173 5.8385e-06
synthetic complete for BY4743 0 4.69543 0.0091345
mncl2 2 mM 4.64469 2.469e-05
myriocin 0.2 ug/ml 4.24355 0.0002443
cadmium chloride 7.81 uM 3.5156 0.0006327
fk506 0.05 ug/ml 2.86742 0.0035287

More... (click to see all Homozygous data)





Section 2: Co-fitness interactions.
Gene-gene relationships for YOL030W

Top 10 functional gene interactors with YOL030W. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.



Heterozygous co-fitness interactions

Top 10 interactors with GAS5 by heterozygous co-sensitivity:

Query Interactor Correlation
GAS5 SFH5 0.37326
GAS5 YOL085C 0.34818
GAS5 YOR059C 0.34447
GAS5 PFA4 0.34112
GAS5 ISW2 0.3406
GAS5 OYE3 0.33648
GAS5 DDI3 0.3335
GAS5 YJR129C 0.33231
GAS5 THI20 0.33108
GAS5 YOL075C 0.3294

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:
  • None
Component:
  • None
 
Homozygous co-fitness interactions

Top 10 interactors with GAS5 by homozygous co-sensitivity:

Query Interactor Correlation
GAS5 YOL029C 0.82221
GAS5 YPR014C 0.78741
GAS5 AVT7 0.75454
GAS5 YOR343C 0.75241
GAS5 RNP1 0.73415
GAS5 KNS1 0.73107
GAS5 FMS1 0.73001
GAS5 AHT1 0.72989
GAS5 YHR126C 0.7264
GAS5 DBP1 0.72618

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:Component:




External information about YOL030W

Other databases:

Visit YOL030W in [ SGD | TheBioGrid | BioPixie ]


Previously known GO terms:
Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.


Download a plain text version of this page.