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YNR052C / POP2

Section 1: Phenotypes.
Gene-drug relationships for YNR052C
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YNR052C deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

Heterozygous knockout:

Top 10 sensitivity-inducing conditions for POP2 Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
no drug minimal media 0 94.6087 1.2522e-09
no drug minimal media 0 92.3974 1.4091e-09
no drug minimal media 0 80.6306 2.7817e-09
no drug minimal media 0 72.9866 2.226e-10
no drug minimal media 0 63.4108 9.2337e-09
no drug minimal media 0 62.9193 9.5996e-09
no drug minimal media 0 53.5278 1.427e-09
no drug minimal media 0 33.2295 2.4715e-08
latrunculin 3.91 uM 32.9633 < 1e-12
latrunculin 1.95 uM 30.2627 < 1e-12

More... (click to see all Heterozygous data)

Homozygous knockout:

Top 10 sensitivity-inducing conditions for POP2 Homozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
rapamycin 9 nM 17.1645 0.0016885
latrunculin 0.78 uM 16.5145 0.0018233
latrunculin 0.78 uM 13.1668 5.5866e-11
potassium disulfite 2500 uM 10.0427 4.1817e-09
licl 100 mM 9.05096 2.0244e-08
nocodazole 10 ug/ml 8.66176 3.8804e-08
rapamycin 9 nM 7.58028 0.0084809
nocodazole 10 ug/ml 7.08532 6.6006e-07
synthetic complete for BY4743 0 6.97134 0.0099811
papuamide b 0.7 ug/ml 5.97413 5.9419e-06

More... (click to see all Homozygous data)

Section 2: Co-fitness interactions.
Gene-gene relationships for YNR052C

Top 10 functional gene interactors with YNR052C. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.

Heterozygous co-fitness interactions

Top 10 interactors with POP2 by heterozygous co-sensitivity:

Query Interactor Correlation
POP2 CCR4 0.65883
POP2 RIB2 0.63631
POP2 RFA2 0.63366
POP2 YGL074C 0.61762
POP2 SEC62 0.61163
POP2 CDC36 0.61114
POP2 YPR085C 0.60355
POP2 YML6 0.598
POP2 SPT10 0.59457
POP2 YJR018W 0.58455

More... (click to see all interactions)

Enriched GO terms of interactors

  • None
  • None
  • None
Homozygous co-fitness interactions

[No homozygous results.]

External information about YNR052C

Other databases:

Visit YNR052C in [ SGD | TheBioGrid | BioPixie ]

Previously known GO terms:
Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.

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