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YNR024W / YNR024W



Section 1: Phenotypes.
Gene-drug relationships for YNR024W
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YNR024W deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

.
Heterozygous knockout:

Top 10 sensitivity-inducing conditions for YNR024W Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
no drug minimal media 0 28.9316 5.648e-08
no drug minimal media 0 25.4742 1.2055e-07
no drug minimal media 0 21.6064 1.9699e-06
no drug minimal media 0 20.5047 2.5527e-06
no drug minimal media 0 18.4446 4.3087e-06
no drug minimal media 0 17.5934 1.0821e-06
no drug minimal media 0 16.7803 6.8689e-06
no drug minimal media 0 16.524 7.4099e-06
no drug minimal media 0 15.7283 2.0934e-06
dyclonine 500 uM 9.66369 2.1018e-12

More... (click to see all Heterozygous data)

 
Homozygous knockout:

Top 10 sensitivity-inducing conditions for YNR024W Homozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
licl 100 mM 12.465 1.3649e-10
synthetic complete for BY4743 0 9.58285 0.0012056
5-fluorouracil 38.46 uM 9.01671 2.0348e-06
5-fluorouracil 19.2 uM 8.70755 2.7818e-06
methotrexate 250 uM 7.97235 9.4371e-09
5-fluorouracil 38.5 uM 6.31396 5.5043e-07
licl 150 mM 5.76625 8.6644e-07
licl 150 mM 5.7525 9.0285e-07
5-fluorouracil 9.6 uM 5.34343 6.8035e-06
nacl 600 mM 5.21654 4.4968e-06

More... (click to see all Homozygous data)





Section 2: Co-fitness interactions.
Gene-gene relationships for YNR024W

Top 10 functional gene interactors with YNR024W. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.



Heterozygous co-fitness interactions

Top 10 interactors with YNR024W by heterozygous co-sensitivity:

Query Interactor Correlation
YNR024W YSY6 0.42932
YNR024W DOT5 0.35889
YNR024W BDH1 0.35763
YNR024W MSH5 0.34729
YNR024W YSR3 0.3443
YNR024W YOL075C 0.34174
YNR024W DSE4 0.34117
YNR024W ZRG17 0.3386
YNR024W SIP5 0.33767
YNR024W DUS1 0.33419

More... (click to see all interactions)

Enriched GO terms of interactors

Process:Function:Component:
 
Homozygous co-fitness interactions

Top 10 interactors with YNR024W by homozygous co-sensitivity:

Query Interactor Correlation
YNR024W DTD1 0.47704
YNR024W FMP42 0.46117
YNR024W PTC3 0.44226
YNR024W YFR020W 0.43537
YNR024W HTA2 0.43354
YNR024W REX4 0.41703
YNR024W TRM10 0.4107
YNR024W ECM5 0.41057
YNR024W KEL2 0.40813
YNR024W MFA1 0.40802

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:
  • None
Component:
  • None




External information about YNR024W

Other databases:

Visit YNR024W in [ SGD | TheBioGrid | BioPixie ]


Previously known GO terms:
Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.


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