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YNR017W / MAS6

Section 1: Phenotypes.
Gene-drug relationships for YNR017W
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YNR017W deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

Heterozygous knockout:

Top 10 sensitivity-inducing conditions for MAS6 Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
bithionol 75 uM 8.6908 1.3726e-11
bithionol 75 uM 8.48786 2.5679e-11
bithionol 75 uM 8.26263 5.3416e-11
pyrithione zinc 1.95 uM 5.1545 2.4899e-06
cocl2 1250 uM 4.39359 5.7288e-05
5-fluorocytosine 15.6 uM 4.35791 3.5449e-05
no drug minimal media 0 4.04726 0.004926
methotrexate 500 uM 3.81182 0.00029621
parthenolide 125 uM 3.46546 0.00057041
thiram 15.6 uM 3.39851 0.00069459

More... (click to see all Heterozygous data)

Homozygous knockout:

[No Homozygous results.]

Section 2: Co-fitness interactions.
Gene-gene relationships for YNR017W

Top 10 functional gene interactors with YNR017W. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.

Heterozygous co-fitness interactions

Top 10 interactors with MAS6 by heterozygous co-sensitivity:

Query Interactor Correlation
MAS6 TIM44 0.40484
MAS6 YMR134W 0.38543
MAS6 PET8 0.36583
MAS6 TIM17 0.36285
MAS6 YOR218C 0.36139
MAS6 KRE6 0.36116
MAS6 RPA135 0.34822
MAS6 VAS1 0.34706
MAS6 RRB1 0.3451
MAS6 RRP1 0.3414

More... (click to see all interactions)

Enriched GO terms of interactors

  • None
Homozygous co-fitness interactions

[No homozygous results.]

External information about YNR017W

Other databases:

Visit YNR017W in [ SGD | TheBioGrid | BioPixie ]

Previously known GO terms:
Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.

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