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YNL334C / SNO2



Section 1: Phenotypes.
Gene-drug relationships for YNL334C
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YNL334C deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

.
Heterozygous knockout:

Top 10 sensitivity-inducing conditions for SNO2 Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
5-fluorouracil 38.5 uM 4.80127 9.791e-05
no drug minimal media 0 4.20636 0.0042189
floxuridine 3.37 uM 3.60235 0.0011937
cuso4 10000 uM 2.82899 0.0039978
methotrexate 125 uM 2.72037 0.0052269
progesterone 1000 uM 2.68186 0.021861
latrunculin 6.25 uM 2.64129 0.0088911
methotrexate 500 uM 2.62629 0.0065673
dyclonine 500 uM 2.60775 0.011448
5-fluorouracil 38.5 uM 2.55764 0.006912

More... (click to see all Heterozygous data)

 
Homozygous knockout:

Top 10 sensitivity-inducing conditions for SNO2 Homozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
rapamycin 9 nM 10.4759 0.00092855
rapamycin 9 nM 8.58592 0.0066476
minimal media 0 5.67883 2.8298e-06
ph8 0 5.56569 3.8012e-06
methoxsalen 500 uM 5.25861 8.5018e-06
sorbitol 1.5e+06 uM 5.18691 1.0267e-05
rapamycin 9 nM 4.81616 0.020255
mycophenolic acid 125 uM 4.65423 4.1866e-05
nacl 1000 uM 3.88817 0.0015093
synthetic complete for BY4743 400 uM 3.73178 0.0019495

More... (click to see all Homozygous data)





Section 2: Co-fitness interactions.
Gene-gene relationships for YNL334C

Top 10 functional gene interactors with YNL334C. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.



Heterozygous co-fitness interactions

Top 10 interactors with SNO2 by heterozygous co-sensitivity:

Query Interactor Correlation
SNO2 YOR378W 0.67852
SNO2 YNL187W 0.65344
SNO2 YOL083W 0.63445
SNO2 YGR093W 0.62545
SNO2 YKL171W 0.61446
SNO2 FRT2 0.61263
SNO2 GNP1 0.60807
SNO2 SRT1 0.60715
SNO2 PRM10 0.60547
SNO2 GRE1 0.60415

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:Component:
  • None
 
Homozygous co-fitness interactions

Top 10 interactors with SNO2 by homozygous co-sensitivity:

Query Interactor Correlation
SNO2 PPN1 0.67725
SNO2 SAP1 0.5859
SNO2 YKL171W 0.58516
SNO2 SAP4 0.55766
SNO2 YPL035C 0.5566
SNO2 NGL3 0.55658
SNO2 YPL191C 0.55612
SNO2 SMF2 0.54639
SNO2 MCR1 0.54103
SNO2 ROM1 0.5346

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:
  • None
Component:
  • None




External information about YNL334C

Other databases:

Visit YNL334C in [ SGD | TheBioGrid | BioPixie ]


Previously known GO terms:
Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.


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