Retrieving results for YNL315C, please wait...

Yeast Fitness
Database

Quick Search

Enter orf / gene / drug:

(e.g. pex22 or lovastatin)  
Advanced search

YNL315C / ATP11



Section 1: Phenotypes.
Gene-drug relationships for YNL315C
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YNL315C deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

.
Heterozygous knockout:

Top 10 sensitivity-inducing conditions for ATP11 Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
metergoline 250 uM 5.55408 6.3233e-07
alverine citrate 500 uM 4.98264 0.018999
dna protein kinase inhibitor 0 4.90583 1.3062e-05
mechlorethamine 250 uM 4.66418 1.2962e-05
itraconazole 17.7 uM 4.41842 2.911e-05
cantharidin 250 uM 4.38618 0.024124
cantharidin 250 uM 4.33807 0.024623
fluconazole 65.3 uM 4.33267 3.8475e-05
no drug minimal media 0 4.32127 0.0024879
alverine citrate 500 uM 4.31302 0.024889

More... (click to see all Heterozygous data)

 
Homozygous knockout:

Top 10 sensitivity-inducing conditions for ATP11 Homozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
mms 0.002 % 61.1059 0.00013385
rapamycin 9 nM 40.8392 0.00029952
rapamycin 9 nM 32.0875 0.00048492
potassium disulfite 2500 uM 13.6232 3.1907e-11
rapamycin 9 nM 12.702 0.0030705
latrunculin 0.78 uM 11.0726 0.004029
angelicin 62.5 uM 10.7372 1.4783e-09
synthetic complete for BY4743 0 9.62121 0.0011916
licl 100 mM 7.57814 2.6273e-07
curcumin 150 uM 5.45757 1.7433e-05

More... (click to see all Homozygous data)





Section 2: Co-fitness interactions.
Gene-gene relationships for YNL315C

Top 10 functional gene interactors with YNL315C. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.



Heterozygous co-fitness interactions

Top 10 interactors with ATP11 by heterozygous co-sensitivity:

Query Interactor Correlation
ATP11 RMP1 0.66267
ATP11 RPG1 0.63727
ATP11 PRP2 0.63538
ATP11 TMA23 0.63333
ATP11 YCR064C 0.6323
ATP11 NPT1 0.61103
ATP11 COQ9 0.60635
ATP11 MPS1 0.60544
ATP11 RIB7 0.60127
ATP11 PGA3 0.59947

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:Component:
  • None
 
Homozygous co-fitness interactions

[No homozygous results.]




External information about YNL315C

Other databases:

Visit YNL315C in [ SGD | TheBioGrid | BioPixie ]


Previously known GO terms:
Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.


Download a plain text version of this page.