Retrieving results for YNL304W, please wait...

Yeast Fitness
Database

Quick Search

Enter orf / gene / drug:

(e.g. pex22 or lovastatin)  
Advanced search

YNL304W / YPT11



Section 1: Phenotypes.
Gene-drug relationships for YNL304W
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YNL304W deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

.
Heterozygous knockout:

Top 10 sensitivity-inducing conditions for YPT11 Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
ID 652287 500 uM 4.54312 3.7288e-05
alverine citrate 500 uM 3.96418 0.02907
tunicamycin 0.15 uM 3.42341 0.0093844
hexetidine 15.6 uM 3.38627 0.00071992
chemical diversity labs 3f2 12.5 uM 3.26579 0.0013023
methotrexate 250 uM 3.12984 0.0015019
lapachol 500 uM 3.08341 0.0017103
trifluoperazine dihydrochloride 31.25 uM 3.05641 0.0022478
myriocin 0.15 ug/ml 3.04193 0.002333
5-fluorouracil 38.5 uM 2.89281 0.0028845

More... (click to see all Heterozygous data)

 
Homozygous knockout:

Top 10 sensitivity-inducing conditions for YPT11 Homozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
methoxsalen 500 uM 6.19598 7.4401e-07
licl 100 mM 6.00831 5.5399e-06
ph4 7.5 5.8963 6.9731e-06
synthetic complete for BY4743 0 4.67917 0.021382
methotrexate 250 uM 4.47845 6.6579e-05
ph4 7.5 4.19928 0.00026954
benzaldehyde 0.003 % 4.14463 0.00030435
synthetic complete for BY4743 0 3.659 0.033623
4nqo 0.0313 uM 3.52593 0.0012068
sorbitol 1.5e+06 uM 3.48179 0.00088823

More... (click to see all Homozygous data)





Section 2: Co-fitness interactions.
Gene-gene relationships for YNL304W

Top 10 functional gene interactors with YNL304W. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.



Heterozygous co-fitness interactions

Top 10 interactors with YPT11 by heterozygous co-sensitivity:

Query Interactor Correlation
YPT11 YNR018W 0.50003
YPT11 COS10 0.49861
YPT11 SKP2 0.49664
YPT11 SPO12 0.4942
YPT11 YJR024C 0.49115
YPT11 SPG4 0.48829
YPT11 YML096W 0.48675
YPT11 YDL057W 0.48637
YPT11 YDL009C 0.4853
YPT11 TEL1 0.48458

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:
  • None
Component:
  • None
 
Homozygous co-fitness interactions

Top 10 interactors with YPT11 by homozygous co-sensitivity:

Query Interactor Correlation
YPT11 YDL177C 0.53294
YPT11 YAT2 0.53247
YPT11 AGX1 0.50697
YPT11 YEF1 0.50375
YPT11 DLD3 0.49883
YPT11 DOG2 0.49733
YPT11 YDL218W 0.49285
YPT11 YFL054C 0.48805
YPT11 DOG1 0.48801
YPT11 YFL042C_p 0.48286

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:Component:
  • None




External information about YNL304W

Other databases:

Visit YNL304W in [ SGD | TheBioGrid | BioPixie ]


Previously known GO terms:
Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.


Download a plain text version of this page.