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Yeast Fitness

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YNL153C / GIM3

Section 1: Phenotypes.
Gene-drug relationships for YNL153C
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YNL153C deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

Heterozygous knockout:

Top 10 sensitivity-inducing conditions for GIM3 Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
methotrexate 500 uM 5.69216 1.3256e-06
dihydromotuporamine C 15 uM 5.20658 5.4476e-06
sodium sulfate 625 uM 4.95141 1.1442e-05
thiabendazole 500 uM 4.40388 3.0524e-05
thiabendazole 500 uM 4.30299 4.2356e-05
thiabendazole 250 uM 3.91492 0.00014544
latrunculin 3.91 uM 3.80568 0.0003013
methotrexate 125 uM 3.36015 0.0010138
no drug minimal media 0 3.01609 0.014774
cuso4 10000 uM 2.90794 0.0032804

More... (click to see all Heterozygous data)

Homozygous knockout:

[No Homozygous results.]

Section 2: Co-fitness interactions.
Gene-gene relationships for YNL153C

Top 10 functional gene interactors with YNL153C. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.

Heterozygous co-fitness interactions

Top 10 interactors with GIM3 by heterozygous co-sensitivity:

Query Interactor Correlation
GIM3 YPT32 0.55705
GIM3 YKR015C 0.52226
GIM3 CWC23 0.51167
GIM3 KAP95 0.49936
GIM3 CDC1 0.49713
GIM3 YGL015C 0.49391
GIM3 CDC42 0.48973
GIM3 YPL068C 0.48506
GIM3 SNF3 0.4796
GIM3 POB3 0.4673

More... (click to see all interactions)

Enriched GO terms of interactors

  • None
  • None
  • None
Homozygous co-fitness interactions

[No homozygous results.]

External information about YNL153C

Other databases:

Visit YNL153C in [ SGD | TheBioGrid | BioPixie ]

Previously known GO terms:
Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.

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