Retrieving results for YNL096C, please wait...

Yeast Fitness
Database

Quick Search

Enter orf / gene / drug:

(e.g. pex22 or lovastatin)  
Advanced search

YNL096C / RPS7B



Section 1: Phenotypes.
Gene-drug relationships for YNL096C
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YNL096C deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

.
Heterozygous knockout:

Top 10 sensitivity-inducing conditions for RPS7B Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
drofenine hydrochloride 750 uM 6.76655 9.2418e-09
methotrexate 500 uM 4.24597 0.0040615
latrunculin 6.25 uM 3.4729 0.001569
dihydromotuporamine C 15 uM 3.36871 0.00099097
methotrexate 500 uM 3.18088 0.0016277
methotrexate 500 uM 3.17193 0.0016662
fluconazole 130.6 uM 3.16659 0.0013541
methotrexate 500 uM 2.94403 0.0029947
propiomazine maleate 500 uM 2.78156 0.0038808
hgcl2 7.81 uM 2.5566 0.0077584

More... (click to see all Heterozygous data)

 
Homozygous knockout:

Top 10 sensitivity-inducing conditions for RPS7B Homozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
rapamycin 9 nM 9.90802 0.0050167
rapamycin 9 nM 8.46613 0.0068332
potassium disulfite 2500 uM 6.33879 2.8367e-06
rapamycin 9 nM 5.00424 0.0076784
licl 100 mM 4.80183 7.1413e-05
myriocin 0.2 ug/ml 3.85491 0.00058018
synthetic complete for BY4743 0 3.49503 0.036506
norcantharidin 2500 uM 2.96933 0.0027196
no drug irradiated 0 2.88002 0.004983
synthetic complete for BY4743 0 2.64924 0.038522

More... (click to see all Homozygous data)





Section 2: Co-fitness interactions.
Gene-gene relationships for YNL096C

Top 10 functional gene interactors with YNL096C. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.



Heterozygous co-fitness interactions

Top 10 interactors with RPS7B by heterozygous co-sensitivity:

Query Interactor Correlation
RPS7B RPS29B 0.59261
RPS7B RPS11B 0.57946
RPS7B BUB1 0.57548
RPS7B RPS4A 0.57276
RPS7B RPS19A 0.55205
RPS7B RPS20 0.54816
RPS7B RPS16A 0.54784
RPS7B RPS16B 0.54452
RPS7B RPS10A 0.5422
RPS7B RPS18A 0.54194

More... (click to see all interactions)

Enriched GO terms of interactors

Process:Function:Component:
 
Homozygous co-fitness interactions

Top 10 interactors with RPS7B by homozygous co-sensitivity:

Query Interactor Correlation
RPS7B RPS28A 0.70116
RPS7B RPS22B 0.6726
RPS7B YLR366W 0.65974
RPS7B YDL062W 0.64034
RPS7B RPS17B 0.63901
RPS7B YLL044W 0.62883
RPS7B RPS26B 0.62195
RPS7B RPS27A 0.6199
RPS7B RPS14A 0.6103
RPS7B YDL063C 0.60717

More... (click to see all interactions)

Enriched GO terms of interactors

Process:Function:Component:




External information about YNL096C

Other databases:

Visit YNL096C in [ SGD | TheBioGrid | BioPixie ]


Previously known GO terms:
Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.


Download a plain text version of this page.