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YNL002C / RLP7

Section 1: Phenotypes.
Gene-drug relationships for YNL002C
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YNL002C deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

Heterozygous knockout:

Top 10 sensitivity-inducing conditions for RLP7 Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
cantharidin 250 uM 6.31753 0.012076
5-fluorocytosine 15.6 uM 5.64292 4.6515e-07
5-fluorouracil 125 uM 5.4021 1.0673e-06
5-fluorocytosine 15.6 uM 5.20719 2.0806e-06
amphotericin b 0.62 uM 5.17224 2.3439e-06
methotrexate 125 uM 5.08222 7.8232e-06
5-fluorouracil 76.8 uM 4.47498 4.536e-05
5-fluorouracil 19.2 uM 4.46872 2.4696e-05
miconazole 100 uM 4.40395 3.0517e-05
5-fluorouracil 38.5 uM 4.29459 4.3522e-05

More... (click to see all Heterozygous data)

Homozygous knockout:

[No Homozygous results.]

Section 2: Co-fitness interactions.
Gene-gene relationships for YNL002C

Top 10 functional gene interactors with YNL002C. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.

Heterozygous co-fitness interactions

Top 10 interactors with RLP7 by heterozygous co-sensitivity:

Query Interactor Correlation
RLP7 NOP2 0.64356
RLP7 RRP46 0.54326
RLP7 NOG2 0.52546
RLP7 RLP24 0.51759
RLP7 MRT4 0.51445
RLP7 NOC2 0.50649
RLP7 MTR3 0.50462
RLP7 NOG1 0.49913
RLP7 YCL053C_d 0.48418
RLP7 RPL6B 0.46906

More... (click to see all interactions)

Enriched GO terms of interactors

Homozygous co-fitness interactions

[No homozygous results.]

External information about YNL002C

Other databases:

Visit YNL002C in [ SGD | TheBioGrid | BioPixie ]

Previously known GO terms:
Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.

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