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Yeast Fitness
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YMR236W / TAF9



Section 1: Phenotypes.
Gene-drug relationships for YMR236W
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YMR236W deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

.
Heterozygous knockout:

Top 10 sensitivity-inducing conditions for TAF9 Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
no drug minimal media 0 4.9654 0.0021142
methotrexate 500 uM 4.83139 1.621e-05
fenpropimorph 8 nM 4.79111 8.4921e-06
no drug minimal media 0 4.73856 0.0025783
methotrexate 500 uM 4.61275 3.0509e-05
clotrimazole 1 uM 4.4949 2.2665e-05
dihydromotuporamine C 15 uM 4.09801 0.00013286
atorvastatin 125 uM 3.84298 0.00018188
aminophenazone 250 uM 3.82173 0.00019423
no drug minimal media 0 3.78817 0.0063912

More... (click to see all Heterozygous data)

 
Homozygous knockout:

[No Homozygous results.]




Section 2: Co-fitness interactions.
Gene-gene relationships for YMR236W

Top 10 functional gene interactors with YMR236W. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.



Heterozygous co-fitness interactions

Top 10 interactors with TAF9 by heterozygous co-sensitivity:

Query Interactor Correlation
TAF9 AEP2 0.73942
TAF9 YMR293C 0.73922
TAF9 RFC3 0.69731
TAF9 RRN9 0.69567
TAF9 ERG28 0.68931
TAF9 PRP24 0.68324
TAF9 PET117 0.68263
TAF9 BUD16 0.67761
TAF9 MTG1 0.66927
TAF9 YOR060C 0.66894

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:
  • None
Component:
  • None
 
Homozygous co-fitness interactions

[No homozygous results.]




External information about YMR236W

Other databases:

Visit YMR236W in [ SGD | TheBioGrid | BioPixie ]


Previously known GO terms:
Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.


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