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Yeast Fitness
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YMR227C / TAF7



Section 1: Phenotypes.
Gene-drug relationships for YMR227C
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YMR227C deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

.
Heterozygous knockout:

Top 10 sensitivity-inducing conditions for TAF7 Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
wiskostatin 29 uM 6.95712 3.5093e-08
methotrexate 500 uM 6.92795 3.8105e-08
latrunculin 3.91 uM 6.76146 6.1055e-08
methotrexate 250 uM 6.64928 8.4004e-08
miconazole 50 nM 6.60951 1.2515e-05
methotrexate 500 uM 6.4746 1.3836e-07
methotrexate 500 uM 6.41125 1.659e-07
caspofungin 10 nM 6.19339 6.8554e-08
latrunculin 6.25 uM 5.77083 1.4332e-05
licl 150 mM 5.70895 1.2625e-06

More... (click to see all Heterozygous data)

 
Homozygous knockout:

[No Homozygous results.]




Section 2: Co-fitness interactions.
Gene-gene relationships for YMR227C

Top 10 functional gene interactors with YMR227C. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.



Heterozygous co-fitness interactions

Top 10 interactors with TAF7 by heterozygous co-sensitivity:

Query Interactor Correlation
TAF7 AEP2 0.54327
TAF7 ERG8 0.52521
TAF7 TAF9 0.52266
TAF7 KRE29 0.51485
TAF7 CEF1 0.50286
TAF7 YMR293C 0.50054
TAF7 CUS1 0.49586
TAF7 HSP10 0.4902
TAF7 YMR185W 0.48093
TAF7 MRE11 0.47116

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:
  • None
Component:
  • None
 
Homozygous co-fitness interactions

[No homozygous results.]




External information about YMR227C

Other databases:

Visit YMR227C in [ SGD | TheBioGrid | BioPixie ]


Previously known GO terms:
Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.


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