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Yeast Fitness
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YMR213W / CEF1



Section 1: Phenotypes.
Gene-drug relationships for YMR213W
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YMR213W deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

.
Heterozygous knockout:

Top 10 sensitivity-inducing conditions for CEF1 Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
methotrexate 250 uM 6.30456 2.2538e-07
aminophenazone 250 uM 5.40911 1.0419e-06
metergoline 250 uM 5.13637 2.6484e-06
hydroxyurea 100000 uM 5.05787 3.4576e-06
clotrimazole 1 uM 4.89811 5.9311e-06
hydroxyurea 50000 uM 4.23249 5.3167e-05
hydroxyurea 25000 uM 4.18399 6.2118e-05
methotrexate 250 uM 4.02421 0.00016359
doxorubicin 62.5 uM 4.0172 0.00010553
5-fluorocytosine 15.6 uM 3.70143 0.00028092

More... (click to see all Heterozygous data)

 
Homozygous knockout:

[No Homozygous results.]




Section 2: Co-fitness interactions.
Gene-gene relationships for YMR213W

Top 10 functional gene interactors with YMR213W. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.



Heterozygous co-fitness interactions

Top 10 interactors with CEF1 by heterozygous co-sensitivity:

Query Interactor Correlation
CEF1 ERG8 0.701
CEF1 AEP2 0.66874
CEF1 ERG28 0.64072
CEF1 ARB1 0.63987
CEF1 YAR1 0.63901
CEF1 CUS1 0.61781
CEF1 TIF11 0.61092
CEF1 PEP5 0.60778
CEF1 PRP16 0.60579
CEF1 SWP1 0.60501

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:
  • None
Component:
  • None
 
Homozygous co-fitness interactions

[No homozygous results.]




External information about YMR213W

Other databases:

Visit YMR213W in [ SGD | TheBioGrid | BioPixie ]


Previously known GO terms:
Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.


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