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YMR149W / SWP1

Section 1: Phenotypes.
Gene-drug relationships for YMR149W
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YMR149W deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

Heterozygous knockout:

Top 10 sensitivity-inducing conditions for SWP1 Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
drofenine hydrochloride 750 uM 12.3674 < 1e-12
fluconazole 65.3 uM 11.1088 < 1e-12
5-fluorocytosine 15.6 uM 5.95047 1.5992e-07
allyl disulfide 0.06 % 5.90301 7.1875e-07
hydroxyurea 25000 uM 5.26908 1.6841e-06
paraquat 2000 uM 5.04427 8.736e-06
dyclonine 500 uM 4.89958 0.0001831
methotrexate 250 uM 4.86096 1.4878e-05
clozapine 500 uM 4.82072 7.6906e-06
methotrexate 500 uM 4.58319 3.3223e-05

More... (click to see all Heterozygous data)

Homozygous knockout:

[No Homozygous results.]

Section 2: Co-fitness interactions.
Gene-gene relationships for YMR149W

Top 10 functional gene interactors with YMR149W. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.

Heterozygous co-fitness interactions

Top 10 interactors with SWP1 by heterozygous co-sensitivity:

Query Interactor Correlation
SWP1 PEP5 0.70191
SWP1 ERG28 0.68814
SWP1 RNA1 0.64803
SWP1 YMR293C 0.63874
SWP1 BUD16 0.63677
SWP1 GUA1 0.63102
SWP1 PET117 0.62062
SWP1 PRP16 0.61922
SWP1 YMR185W 0.61724
SWP1 AEP2 0.61524

More... (click to see all interactions)

Enriched GO terms of interactors

  • None
  • None
  • None
Homozygous co-fitness interactions

[No homozygous results.]

External information about YMR149W

Other databases:

Visit YMR149W in [ SGD | TheBioGrid | BioPixie ]

Previously known GO terms:
Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.

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