Retrieving results for YMR142C, please wait...

Yeast Fitness
Database

Quick Search

Enter orf / gene / drug:

(e.g. pex22 or lovastatin)  
Advanced search

YMR142C / RPL13B



Section 1: Phenotypes.
Gene-drug relationships for YMR142C
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YMR142C deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

.
Heterozygous knockout:

Top 10 sensitivity-inducing conditions for RPL13B Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
23 degrees C 0 3.93562 0.005504
progesterone 1000 uM 2.38236 0.03149
cantharidin 250 uM 1.99379 0.092175
no drug minimal media 0 1.7677 0.063764
nocodazole 6.6 uM 1.65135 0.079789
benomyl 3.4 uM 1.12642 0.15556
cantharidin 250 uM 0.855768 0.24114
5-fluorouracil 19.2 uM 0.828461 0.2098
cantharidin 250 uM 0.793885 0.25525
hygromycin 0.4 uM 0.667309 0.25704

More... (click to see all Heterozygous data)

 
Homozygous knockout:

Top 10 sensitivity-inducing conditions for RPL13B Homozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
potassium disulfite 2500 uM 9.01703 2.141e-08
rapamycin 9 nM 8.24636 0.0071944
synthetic complete for BY4743 0 7.17715 0.0027864
latrunculin 0.78 uM 5.06255 0.018437
bisphenol 125 uM 1.53628 0.070931
psoralen 0.5 uM 1.31051 0.10325
papuamide b 0.37 ug/ml 1.30629 0.10395
papuamide b 0.7 ug/ml 1.28787 0.10705
psoralen 0.5 uM 1.09469 0.14404
no drug irradiated 0 1.0617 0.1512

More... (click to see all Homozygous data)





Section 2: Co-fitness interactions.
Gene-gene relationships for YMR142C

Top 10 functional gene interactors with YMR142C. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.



Heterozygous co-fitness interactions

Top 10 interactors with RPL13B by heterozygous co-sensitivity:

Query Interactor Correlation
RPL13B RPS5 0.4549
RPL13B RPL20B 0.45428
RPL13B ECM15 0.43769
RPL13B SUI2 0.42291
RPL13B RPL19B 0.41136
RPL13B RPL5 0.39963
RPL13B OPI11 0.39691
RPL13B CCT6 0.39283
RPL13B CCT7 0.39237
RPL13B RPL6B 0.38818

More... (click to see all interactions)

Enriched GO terms of interactors

Process:Function:Component:
 
Homozygous co-fitness interactions

[No homozygous results.]




External information about YMR142C

Other databases:

Visit YMR142C in [ SGD | TheBioGrid | BioPixie ]


Previously known GO terms:
Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.


Download a plain text version of this page.