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YLR186W / EMG1

Section 1: Phenotypes.
Gene-drug relationships for YLR186W
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YLR186W deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

Heterozygous knockout:

Top 10 sensitivity-inducing conditions for EMG1 Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
drofenine hydrochloride 750 uM 7.66536 4.0555e-10
econazole nitrate 0.24 uM 6.33024 4.2501e-08
fenpropimorph 4.7 uM 5.99716 1.3592e-07
wiskostatin 29 uM 5.84727 8.4485e-07
wiskostatin 29 uM 5.35869 3.4983e-06
fenpropimorph 4.7 uM 4.46728 2.4813e-05
fluconazole 31.25 uM 4.38408 3.2558e-05
fluconazole 31.25 uM 4.33252 3.8494e-05
itraconazole 8.8 uM 4.25402 4.9609e-05
amphotericin b 0.31 uM 4.21562 5.6128e-05

More... (click to see all Heterozygous data)

Homozygous knockout:

[No Homozygous results.]

Section 2: Co-fitness interactions.
Gene-gene relationships for YLR186W

Top 10 functional gene interactors with YLR186W. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.

Heterozygous co-fitness interactions

Top 10 interactors with EMG1 by heterozygous co-sensitivity:

Query Interactor Correlation
EMG1 MAP1 0.42226
EMG1 UTP8 0.40397
EMG1 KRE33 0.40193
EMG1 CWC24 0.36824
EMG1 YDR115W 0.35792
EMG1 MRPS35 0.35602
EMG1 IMP3 0.35063
EMG1 RRN5 0.34596
EMG1 YGR160W 0.34345
EMG1 TIF4631 0.34329

More... (click to see all interactions)

Enriched GO terms of interactors

  • None
  • None
  • None
Homozygous co-fitness interactions

[No homozygous results.]

External information about YLR186W

Other databases:

Visit YLR186W in [ SGD | TheBioGrid | BioPixie ]

Previously known GO terms:
Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.

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