Retrieving results for YLR048W, please wait...

Yeast Fitness
Database

Quick Search

Enter orf / gene / drug:

(e.g. pex22 or lovastatin)  
Advanced search

YLR048W / RPS0B



Section 1: Phenotypes.
Gene-drug relationships for YLR048W
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YLR048W deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

.
Heterozygous knockout:

Top 10 sensitivity-inducing conditions for RPS0B Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
cantharidin 250 uM 11.6566 0.0036397
cantharidin 250 uM 8.48548 0.0068027
cantharidin 250 uM 8.02929 0.0075797
cantharidin 250 uM 7.61233 0.0084114
cantharidin 250 uM 6.64453 0.010954
methotrexate 250 uM 5.96597 5.989e-07
haloperidol 250 uM 4.16835 6.5306e-05
cuso4 10000 uM 3.93733 0.00020877
fenpropimorph 2.3 uM 3.52912 0.0020766
drofenine hydrochloride 750 uM 3.30533 0.00091082

More... (click to see all Heterozygous data)

 
Homozygous knockout:

Top 10 sensitivity-inducing conditions for RPS0B Homozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
rapamycin 9 nM 9.70241 0.0052283
potassium disulfite 2500 uM 9.07173 1.9564e-08
synthetic complete for BY4743 0 8.65626 0.0016217
licl 100 mM 7.48426 3.1234e-07
licl 100 mM 1.45495 0.081451
rapamycin 9 nM 0.59139 0.29793
papuamide b 0.7 ug/ml 0.364319 0.35993
benomyl 10 ug/ml 0.304866 0.38198
bisphenol 125 uM 0.206459 0.41937
angelicin 62.5 uM 0.182327 0.42868

More... (click to see all Homozygous data)





Section 2: Co-fitness interactions.
Gene-gene relationships for YLR048W

Top 10 functional gene interactors with YLR048W. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.



Heterozygous co-fitness interactions

Top 10 interactors with RPS0B by heterozygous co-sensitivity:

Query Interactor Correlation
RPS0B RPS16B 0.61196
RPS0B RPS29B 0.6088
RPS0B RPS27B 0.59791
RPS0B RRP9 0.59353
RPS0B BUB1 0.58712
RPS0B RPS17A 0.58666
RPS0B RPS11A 0.58661
RPS0B RPS23B 0.58088
RPS0B RPS10A 0.58072
RPS0B RPS6A 0.57728

More... (click to see all interactions)

Enriched GO terms of interactors

Process:Function:Component:
 
Homozygous co-fitness interactions

[No homozygous results.]




External information about YLR048W

Other databases:

Visit YLR048W in [ SGD | TheBioGrid | BioPixie ]


Previously known GO terms:
Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.


Download a plain text version of this page.