Retrieving results for YJR064W, please wait...

Yeast Fitness

Quick Search

Enter orf / gene / drug:

(e.g. pex22 or lovastatin)  
Advanced search

YJR064W / CCT5

Section 1: Phenotypes.
Gene-drug relationships for YJR064W
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YJR064W deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

Heterozygous knockout:

Top 10 sensitivity-inducing conditions for CCT5 Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
cantharidin 250 uM 60.8914 0.0001348
sodium sulfate 625 uM 13.5563 < 1e-12
thiabendazole 250 uM 13.198 < 1e-12
calyculin a 2.5 uM 12.3833 < 1e-12
latrunculin 1.95 uM 12.3527 < 1e-12
itraconazole 4.4 uM 11.7693 < 1e-12
itraconazole 17.7 uM 10.9117 < 1e-12
thiabendazole 500 uM 10.6668 < 1e-12
latrunculin 3.91 uM 9.83099 1.7173e-11
fluconazole 65.3 uM 9.66593 2.0984e-12

More... (click to see all Heterozygous data)

Homozygous knockout:

[No Homozygous results.]

Section 2: Co-fitness interactions.
Gene-gene relationships for YJR064W

Top 10 functional gene interactors with YJR064W. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.

Heterozygous co-fitness interactions

Top 10 interactors with CCT5 by heterozygous co-sensitivity:

Query Interactor Correlation
CCT5 YJL009W 0.76636
CCT5 TCP1 0.68856
CCT5 CCT4 0.66964
CCT5 CCT3 0.66071
CCT5 YDR187C 0.59695
CCT5 CCT6 0.48606
CCT5 CCT2 0.47674
CCT5 CCT7 0.46931
CCT5 ALG12 0.44369
CCT5 TUB3 0.38669

More... (click to see all interactions)

Enriched GO terms of interactors

Homozygous co-fitness interactions

[No homozygous results.]

External information about YJR064W

Other databases:

Visit YJR064W in [ SGD | TheBioGrid | BioPixie ]

Previously known GO terms:
Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.

Download a plain text version of this page.