Retrieving results for YJR001W, please wait...

Yeast Fitness
Database

Quick Search

Enter orf / gene / drug:

(e.g. pex22 or lovastatin)  
Advanced search

YJR001W / AVT1



Section 1: Phenotypes.
Gene-drug relationships for YJR001W
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YJR001W deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

.
Heterozygous knockout:

Top 10 sensitivity-inducing conditions for AVT1 Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
dyclonine 500 uM 7.74466 2.6163e-06
dyclonine 500 uM 5.18226 2.2652e-06
dihydromotuporamine C 15 uM 4.75339 2.032e-05
caspofungin 50 nM 4.17649 6.3627e-05
bithionol 75 uM 3.92832 0.00013948
itraconazole 8.8 uM 3.82434 0.00019267
dyclonine 500 uM 3.7843 0.0013016
fenpropimorph 2.3 uM 3.69381 0.0015352
solasodine 250 uM 3.56904 0.00041908
bithionol 75 uM 3.54944 0.0004444

More... (click to see all Heterozygous data)

 
Homozygous knockout:

Top 10 sensitivity-inducing conditions for AVT1 Homozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
mitomycin c 1000 uM 7.4338 6.3506e-09
mycophenolic acid 125 uM 5.75176 2.3407e-06
tryptophan dropout 0 5.64644 0.00010675
synthetic complete for BY4743 0 5.25095 0.00018644
rapamycin 9 nM 4.88453 0.019725
mitomycin c 1000 uM 4.88308 2.2877e-05
5-fluorouracil 38.5 uM 4.77956 3.0069e-05
23 degrees C 0 4.61604 0.00047818
23 degrees C 0 4.24268 0.00085459
myriocin 0.2 ug/ml 4.23408 0.0002495

More... (click to see all Homozygous data)





Section 2: Co-fitness interactions.
Gene-gene relationships for YJR001W

Top 10 functional gene interactors with YJR001W. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.



Heterozygous co-fitness interactions

Top 10 interactors with AVT1 by heterozygous co-sensitivity:

Query Interactor Correlation
AVT1 SRL3 0.4081
AVT1 UBP1 0.37958
AVT1 YJL055W 0.37736
AVT1 NDI1 0.37479
AVT1 BNA3 0.36806
AVT1 MSC2 0.34797
AVT1 YIL054W 0.34748
AVT1 YDR262W 0.34688
AVT1 YPK2 0.34628
AVT1 YJR008W 0.34545

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:
  • None
Component:
  • None
 
Homozygous co-fitness interactions

Top 10 interactors with AVT1 by homozygous co-sensitivity:

Query Interactor Correlation
AVT1 YGR111W 0.53696
AVT1 YDL177C 0.53287
AVT1 SUT1 0.51082
AVT1 GDH2 0.4946
AVT1 HAM1 0.4885
AVT1 YER079W 0.47849
AVT1 LYS20 0.47762
AVT1 LEU3 0.47686
AVT1 LYS4 0.47077
AVT1 SLF1 0.46991

More... (click to see all interactions)

Enriched GO terms of interactors

Process:Function:
  • None
Component:
  • None




External information about YJR001W

Other databases:

Visit YJR001W in [ SGD | TheBioGrid | BioPixie ]


Previously known GO terms:
Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.


Download a plain text version of this page.