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Yeast Fitness

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YJL167W / ERG20

Section 1: Phenotypes.
Gene-drug relationships for YJL167W
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YJL167W deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

Heterozygous knockout:

Top 10 sensitivity-inducing conditions for ERG20 Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
methotrexate 500 uM 15.137 < 1e-12
no drug minimal media 0 7.7952 0.00011744
no drug minimal media 0 6.92624 0.00022425
dyclonine 500 uM 5.37136 8.3845e-05
fk506 0.1 ug/ml 4.56623 3.4887e-05
no drug minimal media 0 4.53476 0.0019776
fk506 0.1 ug/ml 4.43151 5.1388e-05
dyclonine 500 uM 4.37214 0.00045438
thiabendazole 250 uM 4.04426 9.689e-05
fluconazole 65.3 uM 3.85985 0.00017261

More... (click to see all Heterozygous data)

Homozygous knockout:

[No Homozygous results.]

Section 2: Co-fitness interactions.
Gene-gene relationships for YJL167W

Top 10 functional gene interactors with YJL167W. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.

Heterozygous co-fitness interactions

Top 10 interactors with ERG20 by heterozygous co-sensitivity:

Query Interactor Correlation
ERG20 MSR1 0.5357
ERG20 ATP15 0.51596
ERG20 YNL260C 0.50602
ERG20 DBP5 0.50259
ERG20 RAI1 0.50192
ERG20 RRN11 0.49737
ERG20 RIC1 0.49597
ERG20 TAF11 0.48859
ERG20 SUB2 0.48458
ERG20 SUI1 0.48325

More... (click to see all interactions)

Enriched GO terms of interactors

  • None
  • None
  • None
Homozygous co-fitness interactions

[No homozygous results.]

External information about YJL167W

Other databases:

Visit YJL167W in [ SGD | TheBioGrid | BioPixie ]

Previously known GO terms:
Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.

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