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YJL090C / DPB11



Section 1: Phenotypes.
Gene-drug relationships for YJL090C
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YJL090C deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

.
Heterozygous knockout:

Top 10 sensitivity-inducing conditions for DPB11 Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
methotrexate 500 uM 12.2912 < 1e-12
bufexamac 1000 uM 5.70829 3.7093e-07
bufexamac 1000 uM 4.36216 3.4963e-05
dihydromotuporamine C 15 uM 3.86802 0.00025335
itraconazole 17.7 uM 3.82577 0.00019182
itraconazole 17.7 uM 3.72458 0.00026177
berberine chloride 125 uM 3.70574 0.00027725
lapachol 500 uM 3.69856 0.00028338
mycophenolic acid 125 uM 3.66975 0.00030932
caspofungin 10 nM 3.54124 0.00045542

More... (click to see all Heterozygous data)

 
Homozygous knockout:

[No Homozygous results.]




Section 2: Co-fitness interactions.
Gene-gene relationships for YJL090C

Top 10 functional gene interactors with YJL090C. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.



Heterozygous co-fitness interactions

Top 10 interactors with DPB11 by heterozygous co-sensitivity:

Query Interactor Correlation
DPB11 KRE29 0.51543
DPB11 SCC2 0.51475
DPB11 HCA4 0.50961
DPB11 YMR293C 0.5048
DPB11 POL2 0.49947
DPB11 RIO2 0.49599
DPB11 BET2 0.49592
DPB11 YOR060C 0.49572
DPB11 MTG1 0.49437
DPB11 PSF2 0.48549

More... (click to see all interactions)

Enriched GO terms of interactors

Process:Function:
  • None
Component:
  • None
 
Homozygous co-fitness interactions

[No homozygous results.]




External information about YJL090C

Other databases:

Visit YJL090C in [ SGD | TheBioGrid | BioPixie ]


Previously known GO terms:
Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.


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