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YJL026W / RNR2



Section 1: Phenotypes.
Gene-drug relationships for YJL026W
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YJL026W deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

.
Heterozygous knockout:

Top 10 sensitivity-inducing conditions for RNR2 Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
no drug minimal media 0 30.424 3.599e-07
no drug minimal media 0 29.6398 4.0984e-07
no drug minimal media 0 26.3118 7.4102e-07
no drug minimal media 0 24.1198 1.1414e-06
no drug minimal media 0 21.8678 2.9869e-07
no drug minimal media 0 20.6931 2.4397e-06
no drug minimal media 0 20.1228 4.8908e-07
no drug minimal media 0 15.0107 2.7536e-06
no drug minimal media 0 13.6001 4.9046e-06
miconazole 0.2 uM 9.74169 1.9743e-08

More... (click to see all Heterozygous data)

 
Homozygous knockout:

[No Homozygous results.]




Section 2: Co-fitness interactions.
Gene-gene relationships for YJL026W

Top 10 functional gene interactors with YJL026W. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.



Heterozygous co-fitness interactions

Top 10 interactors with RNR2 by heterozygous co-sensitivity:

Query Interactor Correlation
RNR2 CKS1 0.47576
RNR2 YDR065W 0.42111
RNR2 SRM1 0.41498
RNR2 ATP4 0.41328
RNR2 APC11 0.41026
RNR2 RRP1 0.38583
RNR2 CTF13 0.38538
RNR2 RPG1 0.38235
RNR2 CWC25 0.37626
RNR2 MRPL8 0.37334

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:
  • None
Component:
  • None
 
Homozygous co-fitness interactions

[No homozygous results.]




External information about YJL026W

Other databases:

Visit YJL026W in [ SGD | TheBioGrid | BioPixie ]


Previously known GO terms:
Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.


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