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YJL002C / OST1



Section 1: Phenotypes.
Gene-drug relationships for YJL002C
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YJL002C deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

.
Heterozygous knockout:

Top 10 sensitivity-inducing conditions for OST1 Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
no drug minimal media 0 83.9341 2.2763e-09
no drug minimal media 0 79.2271 3.0367e-09
no drug minimal media 0 64.6039 8.413e-09
no drug minimal media 0 37.9182 1.2017e-07
no drug minimal media 0 37.4367 1.2808e-07
no drug minimal media 0 23.2742 2.0628e-07
no drug minimal media 0 20.1463 4.857e-07
no drug minimal media 0 12.8013 6.9781e-06
no drug minimal media 0 11.8495 1.0923e-05
dyclonine 500 uM 5.4208 7.7394e-05

More... (click to see all Heterozygous data)

 
Homozygous knockout:

[No Homozygous results.]




Section 2: Co-fitness interactions.
Gene-gene relationships for YJL002C

Top 10 functional gene interactors with YJL002C. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.



Heterozygous co-fitness interactions

Top 10 interactors with OST1 by heterozygous co-sensitivity:

Query Interactor Correlation
OST1 RMD9 0.87298
OST1 SPT10 0.86351
OST1 FAD1 0.84323
OST1 NAB2 0.84232
OST1 YML6 0.83457
OST1 MRPL49 0.83276
OST1 LTV1 0.82456
OST1 HEM14 0.80891
OST1 YPR085C 0.79955
OST1 ATP12 0.7886

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:
  • None
Component:
  • None
 
Homozygous co-fitness interactions

[No homozygous results.]




External information about YJL002C

Other databases:

Visit YJL002C in [ SGD | TheBioGrid | BioPixie ]


Previously known GO terms:
Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.


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