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Yeast Fitness

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YIL144W / TID3

Section 1: Phenotypes.
Gene-drug relationships for YIL144W
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YIL144W deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

Heterozygous knockout:

Top 10 sensitivity-inducing conditions for TID3 Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
5-fluorocytosine 15.6 uM 4.72851 1.0466e-05
itraconazole 8.8 uM 4.31276 4.1037e-05
5-fluorocytosine 15.6 uM 3.61699 0.00036284
amphotericin b 0.62 uM 3.05855 0.0018328
caspofungin 10 nM 2.96091 0.002398
cisplatin 125 uM 2.9573 0.0024218
alverine citrate 500 uM 2.95561 0.048972
itraconazole 8.8 uM 2.8715 0.0030547
alverine citrate 500 uM 2.82728 0.052823
methotrexate 500 uM 2.8098 0.0041931

More... (click to see all Heterozygous data)

Homozygous knockout:

[No Homozygous results.]

Section 2: Co-fitness interactions.
Gene-gene relationships for YIL144W

Top 10 functional gene interactors with YIL144W. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.

Heterozygous co-fitness interactions

Top 10 interactors with TID3 by heterozygous co-sensitivity:

Query Interactor Correlation
TID3 BCS1 0.37027
TID3 YLR202C 0.32629
TID3 SNG1 0.32214
TID3 CHS2 0.31986
TID3 SPT20 0.31613
TID3 DIB1 0.30316
TID3 KRE2 0.29611
TID3 HPR1 0.29253
TID3 FMP24 0.29072
TID3 YIL166C 0.28942

More... (click to see all interactions)

Enriched GO terms of interactors

  • None
  • None
  • None
Homozygous co-fitness interactions

[No homozygous results.]

External information about YIL144W

Other databases:

Visit YIL144W in [ SGD | TheBioGrid | BioPixie ]

Previously known GO terms:
Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.

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