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YIL009W / FAA3



Section 1: Phenotypes.
Gene-drug relationships for YIL009W
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YIL009W deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

.
Heterozygous knockout:

Top 10 sensitivity-inducing conditions for FAA3 Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
bufexamac 1000 uM 13.2157 < 1e-12
lapachol 500 uM 7.34913 1.2118e-09
alverine citrate 500 uM 4.80164 0.00021616
bithionol 75 uM 4.72518 1.0583e-05
itraconazole 17.7 uM 4.31299 4.1007e-05
no drug minimal media 0 4.30604 0.0038357
bithionol 75 uM 4.02536 0.00010285
miconazole 50 nM 3.91845 0.0010204
cloxyquin 15.6 uM 3.69226 0.00028887
bithionol 75 uM 3.439 0.00061672

More... (click to see all Heterozygous data)

 
Homozygous knockout:

Top 10 sensitivity-inducing conditions for FAA3 Homozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
mms 0.002 % 6.12661 2.9509e-07
hydroxyurea 100000 uM 5.61924 1.3458e-06
mms 0.002 % 4.5834 0.022226
zncl2 1875 uM 3.81213 0.00027645
cadmium chloride 7.81 uM 3.51094 0.00064088
myriocin 0.2 ug/ml 3.31331 0.001933
methoxsalen 500 uM 3.29225 0.0014318
fk506 0.05 ug/ml 3.08447 0.0020168
synthetic complete for BY4743 0 3.00371 0.047631
5-fluorouracil 19.2 uM 2.77457 0.0098164

More... (click to see all Homozygous data)





Section 2: Co-fitness interactions.
Gene-gene relationships for YIL009W

Top 10 functional gene interactors with YIL009W. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.



Heterozygous co-fitness interactions

Top 10 interactors with FAA3 by heterozygous co-sensitivity:

Query Interactor Correlation
FAA3 NPR1 0.68489
FAA3 RNR3 0.6389
FAA3 PLB1 0.61776
FAA3 TOR1 0.60251
FAA3 IRC9 0.59934
FAA3 DOT5 0.59821
FAA3 YIL092W 0.59617
FAA3 KTR7 0.59548
FAA3 YKL187C 0.59277
FAA3 YOL160W 0.59247

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:
  • None
Component:
  • None
 
Homozygous co-fitness interactions

Top 10 interactors with FAA3 by homozygous co-sensitivity:

Query Interactor Correlation
FAA3 FIT2 0.67855
FAA3 MPC54 0.64094
FAA3 HOP2 0.62752
FAA3 SPO19 0.62663
FAA3 YPR117W 0.6258
FAA3 TAX4 0.61819
FAA3 YOR111W 0.61211
FAA3 YOL163W 0.60978
FAA3 JLP1 0.6094
FAA3 YKL151C 0.60832

More... (click to see all interactions)

Enriched GO terms of interactors

Process:Function:
  • None
Component:
  • None




External information about YIL009W

Other databases:

Visit YIL009W in [ SGD | TheBioGrid | BioPixie ]


Previously known GO terms:
Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.


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