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YGR290W / YGR290W



Section 1: Phenotypes.
Gene-drug relationships for YGR290W
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YGR290W deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

.
Heterozygous knockout:

Top 10 sensitivity-inducing conditions for YGR290W Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
thiabendazole 250 uM 8.16107 7.4922e-11
fluconazole 65.3 uM 8.0286 1.1707e-10
drofenine hydrochloride 750 uM 8.01564 1.2232e-10
5-fluorocytosine 15.6 uM 7.9274 1.6512e-10
lapachol 500 uM 7.10067 2.8776e-09
lovastatin 154.5 uM 6.64845 1.3967e-08
itraconazole 4.4 uM 5.03554 3.7294e-06
itraconazole 35.4 uM 4.56537 1.7975e-05
methotrexate 250 uM 4.54001 1.9541e-05
cloxyquin 15.6 uM 4.42993 2.8036e-05

More... (click to see all Heterozygous data)

 
Homozygous knockout:

Top 10 sensitivity-inducing conditions for YGR290W Homozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
licl 100 mM 9.50659 9.6724e-09
cadmium chloride 7.81 uM 5.49426 1.9572e-06
licl 150 mM 5.1113 6.1601e-06
licl 150 mM 5.08967 6.5714e-06
mitomycin c 1000 uM 5.08077 6.7486e-06
wiskostatin 29 uM 5.05859 7.2108e-06
mycophenolic acid 125 uM 4.6572 4.154e-05
nitric oxide 800 uM 4.33294 9.7682e-05
ph4 8 4.29653 6.8673e-05
adenine dropout 0 4.1991 0.00030139

More... (click to see all Homozygous data)





Section 2: Co-fitness interactions.
Gene-gene relationships for YGR290W

Top 10 functional gene interactors with YGR290W. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.



Heterozygous co-fitness interactions

Top 10 interactors with YGR290W by heterozygous co-sensitivity:

Query Interactor Correlation
YGR290W KEL3 0.42389
YGR290W PRC1 0.40249
YGR290W YMR258C 0.38773
YGR290W YPR096C 0.37292
YGR290W YPR063C 0.36798
YGR290W MLP1 0.36727
YGR290W YBR232C 0.3656
YGR290W RIF2 0.36479
YGR290W PCL2 0.36128
YGR290W WAR1 0.34895

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:
  • None
Component:
  • None
 
Homozygous co-fitness interactions

Top 10 interactors with YGR290W by homozygous co-sensitivity:

Query Interactor Correlation
YGR290W CDA2 0.53704
YGR290W MMP1 0.52611
YGR290W YLR456W 0.47729
YGR290W YOL162W 0.47224
YGR290W YGR291C 0.47134
YGR290W SPH1 0.4701
YGR290W PHO84 0.44566
YGR290W YOR343C 0.42842
YGR290W GEA1 0.42794
YGR290W ESC8 0.42629

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:
  • None
Component:
  • None




External information about YGR290W

Other databases:

Visit YGR290W in [ SGD | TheBioGrid | BioPixie ]


Previously known GO terms:
    Process:
    • None
    Function:
    • None
    Component:
    • None

Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.


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