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YGR282C / BGL2



Section 1: Phenotypes.
Gene-drug relationships for YGR282C
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YGR282C deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

.
Heterozygous knockout:

Top 10 sensitivity-inducing conditions for BGL2 Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
doxorubicin 62.5 uM 5.12931 2.7128e-06
dyclonine 500 uM 4.20103 0.00061482
chloroacetoxyquinoline 3.9 uM 3.82179 0.00019419
daunorubicin 125 uM 3.7288 0.00025841
miconazole 100 uM 3.35278 0.00079376
hydroxyurea 100000 uM 3.26749 0.0010157
fluconazole 65.3 uM 3.24139 0.0010946
hydroxyurea 50000 uM 3.13459 0.0014819
fluconazole 32.6 uM 3.02948 0.0019864
fenpropimorph 8 nM 3.01321 0.0020776

More... (click to see all Heterozygous data)

 
Homozygous knockout:

Top 10 sensitivity-inducing conditions for BGL2 Homozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
ph8 0 8.38441 3.8939e-06
ph8 0 7.76648 7.6244e-06
ph8 0 5.99719 6.6302e-05
latrunculin 0.78 uM 4.91409 0.019502
rapamycin 6 nM 4.5793 2.9952e-05
mechlorethamine 62.5 uM 4.44844 0.0235
alverine citrate 500 uM 4.38802 8.4495e-05
sanguinarine sulfate 250 uM 4.32846 9.8839e-05
synthetic complete for BY4743 0 4.27587 0.025291
latrunculin 0.78 uM 4.2606 0.025459

More... (click to see all Homozygous data)





Section 2: Co-fitness interactions.
Gene-gene relationships for YGR282C

Top 10 functional gene interactors with YGR282C. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.



Heterozygous co-fitness interactions

Top 10 interactors with BGL2 by heterozygous co-sensitivity:

Query Interactor Correlation
BGL2 HNT2 0.46023
BGL2 TIR4 0.43735
BGL2 YHL008C 0.43323
BGL2 VAB2 0.43233
BGL2 RTT102 0.41642
BGL2 YPL113C 0.41239
BGL2 YIM1 0.40829
BGL2 POX1 0.40819
BGL2 RTN2 0.40766
BGL2 CYC7 0.40416

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:
  • None
Component:
  • None
 
Homozygous co-fitness interactions

Top 10 interactors with BGL2 by homozygous co-sensitivity:

Query Interactor Correlation
BGL2 YPR039W 0.49424
BGL2 ATF1 0.48439
BGL2 YPS1 0.47315
BGL2 YKL033W-A 0.43703
BGL2 MRPL13 0.41591
BGL2 JEM1 0.41226
BGL2 MKC7 0.41186
BGL2 KAR9 0.40336
BGL2 YAP3 0.40169
BGL2 KRE2 0.39991

More... (click to see all interactions)

Enriched GO terms of interactors

Process:Function:
  • None
Component:
  • None




External information about YGR282C

Other databases:

Visit YGR282C in [ SGD | TheBioGrid | BioPixie ]


Previously known GO terms:
Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.


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