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YGR151C / YGR151C



Section 1: Phenotypes.
Gene-drug relationships for YGR151C
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YGR151C deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

.
Heterozygous knockout:

Top 10 sensitivity-inducing conditions for YGR151C Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
no drug minimal media 0 5.1844 0.0017562
cyclamin 62.5 uM 5.07074 8.0887e-06
no drug minimal media 0 4.55577 0.0030402
resveratrol 2000 uM 4.37295 6.0774e-05
no drug minimal media 0 4.03992 0.0049617
amphotericin b 0.31 uM 3.77667 0.00022315
no drug minimal media 0 3.51293 0.0085236
fluconazole 31.25 uM 3.44229 0.00061078
phenolphthalein 250 uM 3.3966 0.00091977
no drug minimal media 0 3.31232 0.010593

More... (click to see all Heterozygous data)

 
Homozygous knockout:

Top 10 sensitivity-inducing conditions for YGR151C Homozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
methotrexate 250 uM 7.04378 8.8247e-08
synthetic complete for BY4743 0 4.90276 0.00087381
cisplatin 250 uM 4.33219 9.7874e-05
synthetic complete for BY4743 0 4.26559 0.0039861
floxuridine 3.37 uM 4.08237 0.00018851
synthetic complete for BY4743 0 3.48478 0.0051001
synthetic complete for BY4743 0 3.39268 0.013731
synthetic complete for BY4743 0 3.3834 0.013849
synthetic complete for BY4743 0 3.20482 0.011933
synthetic complete for BY4743 0 2.97653 0.010308

More... (click to see all Homozygous data)





Section 2: Co-fitness interactions.
Gene-gene relationships for YGR151C

Top 10 functional gene interactors with YGR151C. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.



Heterozygous co-fitness interactions

Top 10 interactors with YGR151C by heterozygous co-sensitivity:

Query Interactor Correlation
YGR151C YLR241W 0.55716
YGR151C FMP25 0.53694
YGR151C THI21 0.53425
YGR151C PEX27 0.5109
YGR151C TES1 0.50355
YGR151C YDR401W 0.49491
YGR151C NUP2 0.49445
YGR151C GSM1 0.49109
YGR151C YLR326W 0.48435
YGR151C RRI2 0.48329

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:
  • None
Component:
  • None
 
Homozygous co-fitness interactions

Top 10 interactors with YGR151C by homozygous co-sensitivity:

Query Interactor Correlation
YGR151C YGR207C 0.50727
YGR151C YGR168C 0.47357
YGR151C PBP2 0.46525
YGR151C YGR205W 0.45475
YGR151C RSR1 0.45351
YGR151C YDL180W 0.45267
YGR151C ATG26 0.44726
YGR151C NYV1 0.4452
YGR151C YHL012W 0.43892
YGR151C SLF1 0.43483

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:
  • None
Component:
  • None




External information about YGR151C

Other databases:

Visit YGR151C in [ SGD | TheBioGrid | BioPixie ]


Previously known GO terms:
    Process:
    • None
    Function:
    • None
    Component:
    • None

Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.


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