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YGR114C / YGR114C



Section 1: Phenotypes.
Gene-drug relationships for YGR114C
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YGR114C deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

.
Heterozygous knockout:

Top 10 sensitivity-inducing conditions for YGR114C Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
amphotericin b 10 uM 5.03499 3.7363e-06
37 degrees C 0 3.78712 0.00021609
37 degrees C 0 3.35225 0.00079499
pp2 100 uM 3.13169 0.0018503
nystatin 5 uM 3.09592 0.0016516
allyl sulfide 0.12 % 2.81771 0.0041115
fecl4 2500 uM 2.79794 0.0043182
wiskostatin 19 uM 2.76805 0.0046493
pp1 100 uM 2.67587 0.0058256
potassium disulfite 2500 uM 2.54023 0.0080657

More... (click to see all Heterozygous data)

 
Homozygous knockout:

[No Homozygous results.]




Section 2: Co-fitness interactions.
Gene-gene relationships for YGR114C

Top 10 functional gene interactors with YGR114C. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.



Heterozygous co-fitness interactions

Top 10 interactors with YGR114C by heterozygous co-sensitivity:

Query Interactor Correlation
YGR114C SPT6 0.60699
YGR114C YOL019W 0.51196
YGR114C RPN7 0.48346
YGR114C SPN1 0.44994
YGR114C YGR115C 0.44707
YGR114C RPS21A 0.44478
YGR114C MOT1 0.43939
YGR114C RPS25A 0.43451
YGR114C PXA2 0.42027
YGR114C TPC1 0.41264

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:
  • None
Component:
  • None
 
Homozygous co-fitness interactions

[No homozygous results.]




External information about YGR114C

Other databases:

Visit YGR114C in [ SGD | TheBioGrid | BioPixie ]


Previously known GO terms:
    Process:
    • None
    Function:
    • None
    Component:
    • None

Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.


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