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Yeast Fitness

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YGR103W / NOP7

Section 1: Phenotypes.
Gene-drug relationships for YGR103W
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YGR103W deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

Heterozygous knockout:

Top 10 sensitivity-inducing conditions for NOP7 Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
dmso 4% 4 uM 3.8788 0.00016275
bithionol 75 uM 3.73297 0.00025514
bithionol 75 uM 3.37817 0.00073716
phenoxybenzamine hydrochloride 500 uM 2.93897 0.0025457
nimustine 1000 uM 2.77666 0.0039313
5-fluorocytosine 15.6 uM 2.62399 0.005842
5-fluorouracil 76.9 uM 2.30701 0.012754
fenpropimorph 2.3 uM 2.26903 0.013949
clotrimazole 2 uM 2.20257 0.016283
benomyl 6.9 uM 2.19198 0.039948

More... (click to see all Heterozygous data)

Homozygous knockout:

[No Homozygous results.]

Section 2: Co-fitness interactions.
Gene-gene relationships for YGR103W

Top 10 functional gene interactors with YGR103W. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.

Heterozygous co-fitness interactions

Top 10 interactors with NOP7 by heterozygous co-sensitivity:

Query Interactor Correlation
NOP7 VPS51 0.57619
NOP7 SDH3 0.52826
NOP7 PCP1 0.52728
NOP7 YFR042W 0.52406
NOP7 OCH1 0.52195
NOP7 YGR102C 0.51547
NOP7 LEA1 0.50628
NOP7 VPH2 0.50259
NOP7 LSM5 0.49299
NOP7 NSA2 0.48786

More... (click to see all interactions)

Enriched GO terms of interactors

  • None
  • None
  • None
Homozygous co-fitness interactions

[No homozygous results.]

External information about YGR103W

Other databases:

Visit YGR103W in [ SGD | TheBioGrid | BioPixie ]

Previously known GO terms:
Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.

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