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Yeast Fitness
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YGR029W / ERV1



Section 1: Phenotypes.
Gene-drug relationships for YGR029W
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YGR029W deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

.
Heterozygous knockout:

Top 10 sensitivity-inducing conditions for ERV1 Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
benomyl 27.6 uM 12.0951 < 1e-12
methotrexate 500 uM 8.52103 4.8767e-10
dna protein kinase inhibitor 0 6.76044 6.1233e-08
thiabendazole 500 uM 5.83106 2.4226e-07
wiskostatin 29 uM 5.46882 2.5386e-06
ketoconazole 11.8 uM 5.44747 2.6854e-05
licl 150 mM 4.96392 1.1034e-05
dyclonine 500 uM 4.85629 6.826e-06
dihydromotuporamine C 15 uM 4.27107 8.1299e-05
5-fluorouracil 38.4 uM 3.70971 0.00039282

More... (click to see all Heterozygous data)

 
Homozygous knockout:

[No Homozygous results.]




Section 2: Co-fitness interactions.
Gene-gene relationships for YGR029W

Top 10 functional gene interactors with YGR029W. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.



Heterozygous co-fitness interactions

Top 10 interactors with ERV1 by heterozygous co-sensitivity:

Query Interactor Correlation
ERV1 ALF1 0.62617
ERV1 YGL069C 0.5566
ERV1 UBP3 0.5507
ERV1 MGE1 0.55016
ERV1 SNU114 0.53939
ERV1 RIO2 0.51738
ERV1 YDR196C 0.51529
ERV1 RSP5 0.51496
ERV1 RRN3 0.51129
ERV1 SRP102 0.51104

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:
  • None
Component:
  • None
 
Homozygous co-fitness interactions

[No homozygous results.]




External information about YGR029W

Other databases:

Visit YGR029W in [ SGD | TheBioGrid | BioPixie ]


Previously known GO terms:
Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.


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