Retrieving results for YGR019W, please wait...

Yeast Fitness
Database

Quick Search

Enter orf / gene / drug:

(e.g. pex22 or lovastatin)  
Advanced search

YGR019W / UGA1



Section 1: Phenotypes.
Gene-drug relationships for YGR019W
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YGR019W deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

.
Heterozygous knockout:

Top 10 sensitivity-inducing conditions for UGA1 Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
methotrexate 500 uM 10.1958 7.0378e-12
methotrexate 500 uM 9.87803 1.5292e-11
itraconazole 17.7 uM 5.76744 3.0215e-07
thiabendazole 500 uM 4.20528 5.8022e-05
lovastatin 62.5 uM 3.40724 0.00067705
nocodazole 6.9 uM 3.01996 0.014709
lovastatin 154.5 uM 2.86956 0.0030706
5-fluorouracil 76.8 uM 2.73007 0.0051041
emodin 1000 uM 2.55318 0.00699
dyclonine 500 uM 2.5464 0.0071102

More... (click to see all Heterozygous data)

 
Homozygous knockout:

Top 10 sensitivity-inducing conditions for UGA1 Homozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
zncl2 1875 uM 3.79016 0.00029415
mechlorethamine 62.5 uM 3.51057 0.036218
wiskostatin 29 uM 2.98546 0.0026089
carboplatin 15 mM 2.4407 0.012612
cadmium chloride 7.81 uM 2.40969 0.010763
mechlorethamine 62.5 uM 2.22586 0.016379
sorbitol 1.5e+06 uM 2.10437 0.022583
synthetic complete for BY4743 0 2.05614 0.054464
allyl disulfide 0.06 % 2.05009 0.024065
mitomycin c 1000 uM 1.82474 0.038418

More... (click to see all Homozygous data)





Section 2: Co-fitness interactions.
Gene-gene relationships for YGR019W

Top 10 functional gene interactors with YGR019W. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.



Heterozygous co-fitness interactions

Top 10 interactors with UGA1 by heterozygous co-sensitivity:

Query Interactor Correlation
UGA1 MDG1 0.59274
UGA1 YHB1 0.59237
UGA1 YCR023C 0.58863
UGA1 YER128W 0.5619
UGA1 YCL002C 0.56066
UGA1 LYS5 0.5585
UGA1 SAK1 0.55563
UGA1 NAS6 0.55448
UGA1 SAS4 0.55394
UGA1 YER091C-A 0.55343

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:
  • None
Component:
  • None
 
Homozygous co-fitness interactions

Top 10 interactors with UGA1 by homozygous co-sensitivity:

Query Interactor Correlation
UGA1 YOR175C 0.7267
UGA1 YOR111W 0.69922
UGA1 HIS3 0.68597
UGA1 BDH1 0.68173
UGA1 ENO1 0.67994
UGA1 CTT1 0.65727
UGA1 IAH1 0.65541
UGA1 YKR015C 0.64962
UGA1 YEH1 0.64864
UGA1 ODC2 0.64835

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:
  • None
Component:
  • None




External information about YGR019W

Other databases:

Visit YGR019W in [ SGD | TheBioGrid | BioPixie ]


Previously known GO terms:
Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.


Download a plain text version of this page.