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YGL214W / YGL214W



Section 1: Phenotypes.
Gene-drug relationships for YGL214W
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YGL214W deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

.
Heterozygous knockout:

Top 10 sensitivity-inducing conditions for YGL214W Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
itraconazole 17.7 uM 6.11177 9.115e-08
drofenine hydrochloride 750 uM 4.09278 8.3085e-05
tryptanthrin 250 uM 4.07388 0.00014222
itraconazole 17.7 uM 3.98094 0.00011828
itraconazole 4.4 uM 3.88489 0.0001597
5-fluorouracil 38.5 uM 3.74872 0.00087625
mechlorethamine 500 uM 3.67692 0.00030265
mechlorethamine 500 uM 3.52893 0.00047246
floxuridine 3.37 uM 3.40468 0.0018121
miconazole 100 uM 3.39558 0.00070058

More... (click to see all Heterozygous data)

 
Homozygous knockout:

Top 10 sensitivity-inducing conditions for YGL214W Homozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
methotrexate 250 uM 5.97685 1.3067e-06
cycloheximide 32.3 uM 5.41067 2.5143e-06
allyl disulfide 0.06 % 5.1464 5.5465e-06
cocl2 1250 uM 5.09633 6.442e-06
synthetic complete for BY4743 0 4.94566 0.00029113
potassium disulfite 2500 uM 4.93686 5.3229e-05
streptovitacin 31.25 uM 4.55256 3.241e-05
cadmium chloride 7.81 uM 4.23378 8.2439e-05
hygromycin 13.75 uM 4.05014 0.0001402
synthetic complete for BY4743 0 3.81337 0.0017052

More... (click to see all Homozygous data)





Section 2: Co-fitness interactions.
Gene-gene relationships for YGL214W

Top 10 functional gene interactors with YGL214W. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.



Heterozygous co-fitness interactions

Top 10 interactors with YGL214W by heterozygous co-sensitivity:

Query Interactor Correlation
YGL214W VAB2 0.56902
YGL214W GYP5 0.51434
YGL214W YMR194C-A 0.50621
YGL214W YOR366W 0.50584
YGL214W MIC17 0.49491
YGL214W YLL059C 0.49319
YGL214W DON1 0.4931
YGL214W GYP6 0.49038
YGL214W YHL005C 0.48432
YGL214W EMP70 0.48381

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:
  • None
Component:
  • None
 
Homozygous co-fitness interactions

Top 10 interactors with YGL214W by homozygous co-sensitivity:

Query Interactor Correlation
YGL214W SKI3 0.76171
YGL214W SKI8 0.68416
YGL214W SKI2 0.59888
YGL214W SKI7 0.59852
YGL214W RPL9B 0.55527
YGL214W DBP3 0.5384
YGL214W RPL31B 0.536
YGL214W GPR1 0.53198
YGL214W APT2 0.51751
YGL214W RPL24B 0.51457

More... (click to see all interactions)

Enriched GO terms of interactors

Process:Function:Component:




External information about YGL214W

Other databases:

Visit YGL214W in [ SGD | TheBioGrid | BioPixie ]


Previously known GO terms:
    Process:
    • None
    Function:
    • None
    Component:
    • None

Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.


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