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YGL065C / ALG2



Section 1: Phenotypes.
Gene-drug relationships for YGL065C
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YGL065C deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

.
Heterozygous knockout:

Top 10 sensitivity-inducing conditions for ALG2 Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
dmso 4% 4 uM 5.9415 1.6499e-07
dihydromotuporamine C 15 uM 5.73965 1.1547e-06
nacl 700 mM 5.45383 2.6519e-06
latrunculin 3.91 uM 4.70723 2.3223e-05
benzyl benzoate 1000 uM 4.61601 1.5206e-05
aminophenazone 250 uM 4.37786 3.3223e-05
tryptanthrin 250 uM 4.18329 0.00010435
nimustine 1000 uM 3.98307 0.00011749
thiabendazole 500 uM 3.53018 0.0004707
caspofungin 10 nM 3.51208 0.00049678

More... (click to see all Heterozygous data)

 
Homozygous knockout:

[No Homozygous results.]




Section 2: Co-fitness interactions.
Gene-gene relationships for YGL065C

Top 10 functional gene interactors with YGL065C. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.



Heterozygous co-fitness interactions

Top 10 interactors with ALG2 by heterozygous co-sensitivity:

Query Interactor Correlation
ALG2 DUO1 0.74603
ALG2 SCC2 0.67367
ALG2 SRP21 0.67211
ALG2 YDR196C 0.66984
ALG2 KAR1 0.66356
ALG2 BRR2 0.65241
ALG2 MCT1 0.65188
ALG2 SNU114 0.64989
ALG2 RIB7 0.64873
ALG2 PRP24 0.6454

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:
  • None
Component:
  • None
 
Homozygous co-fitness interactions

[No homozygous results.]




External information about YGL065C

Other databases:

Visit YGL065C in [ SGD | TheBioGrid | BioPixie ]


Previously known GO terms:
Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.


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