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YGL007W / YGL007W



Section 1: Phenotypes.
Gene-drug relationships for YGL007W
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YGL007W deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

.
Heterozygous knockout:

Top 10 sensitivity-inducing conditions for YGL007W Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
no drug minimal media 0 12.4809 2.9284e-05
no drug minimal media 0 10.8503 5.7721e-05
no drug minimal media 0 10.6986 6.1777e-05
no drug minimal media 0 9.85484 9.1679e-05
no drug minimal media 0 7.14157 0.00041797
no drug minimal media 0 7.05346 0.00020317
no drug minimal media 0 5.02883 0.0011915
no drug minimal media 0 4.16274 0.0029631
dmso 4% 4 uM 4.09748 8.1854e-05
atorvastatin 125 uM 3.70194 0.00028048

More... (click to see all Heterozygous data)

 
Homozygous knockout:

Top 10 sensitivity-inducing conditions for YGL007W Homozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
synthetic complete for BY4743 0 30.2761 3.6874e-07
synthetic complete for BY4743 0 27.2203 1.1584e-08
synthetic complete for BY4743 0 24.945 9.6584e-07
synthetic complete for BY4743 0 24.0038 2.7701e-08
synthetic complete for BY4743 0 23.4707 3.2361e-08
synthetic complete for BY4743 0 23.1161 3.5956e-08
synthetic complete for BY4743 0 22.5704 1.141e-05
synthetic complete for BY4743 0 22.3608 1.1841e-05
synthetic complete for BY4743 0 21.084 2.2238e-06
synthetic complete for BY4743 0 21.0381 2.248e-06

More... (click to see all Homozygous data)





Section 2: Co-fitness interactions.
Gene-gene relationships for YGL007W

Top 10 functional gene interactors with YGL007W. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.



Heterozygous co-fitness interactions

Top 10 interactors with YGL007W by heterozygous co-sensitivity:

Query Interactor Correlation
YGL007W MST27 0.54987
YGL007W YGL138C 0.54944
YGL007W YGR016W 0.54184
YGL007W YGL132W 0.49132
YGL007W CTF19 0.48717
YGL007W SAS5 0.47693
YGL007W LIP5 0.46015
YGL007W IRC4 0.45282
YGL007W VBA3 0.44977
YGL007W RPL1B 0.43975

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:
  • None
Component:
  • None
 
Homozygous co-fitness interactions

Top 10 interactors with YGL007W by homozygous co-sensitivity:

Query Interactor Correlation
YGL007W PTK2 0.65062
YGL007W SKY1 0.64301
YGL007W ACB1 0.46889
YGL007W IRC13 0.41711
YGL007W HOT13 0.39952
YGL007W ATF2 0.39687
YGL007W YGR025W 0.39684
YGL007W YDR199W 0.39639
YGL007W YPL136W 0.39566
YGL007W YMR1 0.39386

More... (click to see all interactions)

Enriched GO terms of interactors

Process:Function:
  • None
Component:
  • None




External information about YGL007W

Other databases:

Visit YGL007W in [ SGD | TheBioGrid | BioPixie ]


Previously known GO terms:
    Process:
    • None
    Function:
    • None
    Component:
    • None

Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.


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