Retrieving results for YER046W-A, please wait...

Yeast Fitness
Database

Quick Search

Enter orf / gene / drug:

(e.g. pex22 or lovastatin)  
Advanced search

YER046W-A / YER046W-A



Section 1: Phenotypes.
Gene-drug relationships for YER046W-A
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YER046W-A deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

.
Heterozygous knockout:

Top 10 sensitivity-inducing conditions for YER046W-A Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
miconazole 0.2 uM 8.38082 1.5089e-07
tryptanthrin 250 uM 6.51048 1.2485e-07
nacl 700 mM 5.54308 2.0451e-06
itraconazole 17.7 uM 5.40166 1.0689e-06
licl 150 mM 5.23861 4.9625e-06
fluconazole 130.6 uM 4.95212 4.9444e-06
miconazole 25 nM 4.91833 5.5409e-06
methotrexate 500 uM 4.79118 1.8213e-05
itraconazole 17.7 uM 4.44711 2.6506e-05
5-fluorouridine 95 uM 4.43018 2.8014e-05

More... (click to see all Heterozygous data)

 
Homozygous knockout:

Top 10 sensitivity-inducing conditions for YER046W-A Homozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
nocodazole 10 ug/ml 7.7008 2.0996e-07
licl 100 mM 7.37893 3.7977e-07
latrunculin 3 uM 6.7304 1.3078e-06
ph4 8 5.56867 1.566e-06
zncl2 1875 uM 5.41415 2.4883e-06
synthetic complete for BY4743 0 5.07302 0.007396
ph4 8 4.81565 1.4872e-05
mncl2 2 mM 4.66128 2.3508e-05
myriocin 0.2 ug/ml 4.58476 0.00011491
fk506 0.05 ug/ml 4.11398 0.00011664

More... (click to see all Homozygous data)





Section 2: Co-fitness interactions.
Gene-gene relationships for YER046W-A

Top 10 functional gene interactors with YER046W-A. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.



Heterozygous co-fitness interactions

Top 10 interactors with YER046W-A by heterozygous co-sensitivity:

Query Interactor Correlation
YER046W-A HSP10 0.54725
YER046W-A AEP2 0.51814
YER046W-A ERG28 0.51508
YER046W-A ISC1 0.51042
YER046W-A BUD16 0.4994
YER046W-A KRE29 0.49747
YER046W-A YMR293C 0.49547
YER046W-A PAU13 0.49159
YER046W-A PET117 0.49037
YER046W-A YER087W 0.47299

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:
  • None
Component:
  • None
 
Homozygous co-fitness interactions

Top 10 interactors with YER046W-A by homozygous co-sensitivity:

Query Interactor Correlation
YER046W-A GSM1 0.56102
YER046W-A MRL1 0.54386
YER046W-A YOR059C 0.53138
YER046W-A PYC2 0.52337
YER046W-A ALP1 0.51457
YER046W-A YDL177C 0.51367
YER046W-A CRH1 0.51357
YER046W-A YLR456W 0.50248
YER046W-A TDH2 0.49931
YER046W-A YJL068C 0.48755

More... (click to see all interactions)

Enriched GO terms of interactors

Process:Function:Component:
  • None




External information about YER046W-A

Other databases:

Visit YER046W-A in [ SGD | TheBioGrid | BioPixie ]


Previously known GO terms:
    Process:
    • None
    Function:
    • None
    Component:
    • None

Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.


Download a plain text version of this page.