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Yeast Fitness
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YDR029W / YDR029W



Section 1: Phenotypes.
Gene-drug relationships for YDR029W
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YDR029W deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

.
Heterozygous knockout:

Top 10 sensitivity-inducing conditions for YDR029W Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
latrunculin 3.91 uM 3.21922 0.0014722
doxorubicin 62.5 uM 3.04426 0.0019069
zncl2 468.8 uM 2.78587 0.0044492
dihydromotuporamine C 15 uM 2.25604 0.015518
ID 630688 250 uM 2.00279 0.026866
no drug minimal media 0 1.93122 0.055658
pimethixene maleate 125 uM 1.92263 0.030299
5-fluorouridine 47.5 uM 1.78507 0.040352
anisomycin 31.25 uM 1.72949 0.045142
caspofungin 10 nM 1.72476 0.045571

More... (click to see all Heterozygous data)

 
Homozygous knockout:

Top 10 sensitivity-inducing conditions for YDR029W Homozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
mitomycin c 1000 uM 5.69246 1.0807e-06
myriocin 0.2 ug/ml 4.26225 0.00023437
sorbitol 1.5e+06 uM 4.21338 0.00013374
licl 100 mM 3.6256 0.00096693
wiskostatin 29 uM 3.59916 0.00050217
cantharidin 200 uM 3.58666 0.00051988
mechlorethamine 62.5 uM 3.42271 0.0010315
minimal media 0 3.20592 0.0025906
sorbitol 1.5e+06 uM 3.19426 0.0026564
ph8 0 3.06501 0.0025116

More... (click to see all Homozygous data)





Section 2: Co-fitness interactions.
Gene-gene relationships for YDR029W

Top 10 functional gene interactors with YDR029W. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.



Heterozygous co-fitness interactions

Top 10 interactors with YDR029W by heterozygous co-sensitivity:

Query Interactor Correlation
YDR029W YJL007C 0.69062
YDR029W YAL027W 0.6419
YDR029W YJR024C 0.63793
YDR029W YNL092W 0.62532
YDR029W DUR3 0.61798
YDR029W SVS1 0.61454
YDR029W YOL046C 0.61255
YDR029W YGR018C 0.60441
YDR029W GZF3 0.60364
YDR029W RCK1 0.60262

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:
  • None
Component:
  • None
 
Homozygous co-fitness interactions

Top 10 interactors with YDR029W by homozygous co-sensitivity:

Query Interactor Correlation
YDR029W FKH1 0.60782
YDR029W FUN26 0.58437
YDR029W PMT5 0.57966
YDR029W LTP1 0.57674
YDR029W BNS1 0.57255
YDR029W YHR003C 0.56786
YDR029W FMP16 0.56202
YDR029W YPR071W 0.56121
YDR029W YJL055W 0.5609
YDR029W COX9 0.54498

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:
  • None
Component:
  • None




External information about YDR029W

Other databases:

Visit YDR029W in [ SGD | TheBioGrid | BioPixie ]


Previously known GO terms:
    Process:
    • None
    Function:
    • None
    Component:
    • None

Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.


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