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YBR300C / YBR300C



Section 1: Phenotypes.
Gene-drug relationships for YBR300C
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YBR300C deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

.
Heterozygous knockout:

Top 10 sensitivity-inducing conditions for YBR300C Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
miconazole 0.2 uM 9.98855 1.3955e-08
alverine citrate 500 uM 9.44086 0.0055171
alverine citrate 500 uM 8.36432 0.0069971
latrunculin 3.91 uM 7.26037 1.4987e-08
wiskostatin 29 uM 6.63055 8.861e-08
wortmannin 50 uM 6.60142 9.6287e-08
cocl2 1250 uM 6.58836 9.9942e-08
benfluorex hydrochloride 250 uM 6.50945 1.2522e-07
methotrexate 500 uM 6.25995 2.5625e-07
aphidicolin glycinate 125 uM 6.02093 5.1082e-07

More... (click to see all Heterozygous data)

 
Homozygous knockout:

Top 10 sensitivity-inducing conditions for YBR300C Homozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
wiskostatin 29 uM 32.4518 < 1e-12
allyl disulfide 0.06 % 16.4702 < 1e-12
cadmium chloride 7.81 uM 15.4015 < 1e-12
phosphatase inhibitor 3 uM 14.9927 < 1e-12
zncl2 1875 uM 13.1507 < 1e-12
cocl2 1250 uM 11.1489 < 1e-12
sodium sulfate 625 uM 10.9774 < 1e-12
hydroxyurea 100000 uM 9.34488 3.2112e-11
ph4 8 8.8886 1.0889e-10
37 degrees C 0 8.78621 1.4593e-09

More... (click to see all Homozygous data)





Section 2: Co-fitness interactions.
Gene-gene relationships for YBR300C

Top 10 functional gene interactors with YBR300C. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.



Heterozygous co-fitness interactions

Top 10 interactors with YBR300C by heterozygous co-sensitivity:

Query Interactor Correlation
YBR300C PHO89 0.62765
YBR300C YLR232W 0.5916
YBR300C SOL2 0.57877
YBR300C RHB1 0.57496
YBR300C PCA1 0.55443
YBR300C MAL31 0.55428
YBR300C YCR049C 0.55336
YBR300C YCR085W 0.54444
YBR300C YCR043C 0.54306
YBR300C SRB8 0.54068

More... (click to see all interactions)

Enriched GO terms of interactors

Process:Function:Component:
  • None
 
Homozygous co-fitness interactions

Top 10 interactors with YBR300C by homozygous co-sensitivity:

Query Interactor Correlation
YBR300C YBR292C 0.78952
YBR300C YCR085W 0.7522
YBR300C YCR025C 0.7194
YBR300C YKL023W 0.71444
YBR300C YBR284W 0.70666
YBR300C PCA1 0.70185
YBR300C NOP13 0.68427
YBR300C LUG1 0.68149
YBR300C PMP1 0.67156
YBR300C YDL025C 0.66566

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:
  • None
Component:
  • None




External information about YBR300C

Other databases:

Visit YBR300C in [ SGD | TheBioGrid | BioPixie ]


Previously known GO terms:
    Process:
    • None
    Function:
    • None
    Component:
    • None

Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.


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