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YBR292C / YBR292C



Section 1: Phenotypes.
Gene-drug relationships for YBR292C
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YBR292C deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

.
Heterozygous knockout:

Top 10 sensitivity-inducing conditions for YBR292C Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
drofenine hydrochloride 750 uM 22.3019 < 1e-12
propiomazine maleate 500 uM 21.4914 < 1e-12
caspofungin 10 nM 21.3856 < 1e-12
wiskostatin 29 uM 19.3152 < 1e-12
metergoline 250 uM 18.5707 < 1e-12
hexetidine 31.25 uM 18.5688 < 1e-12
benomyl 6.9 uM 18.3531 4.4158e-06
fendiline hydrochloride 125 uM 17.7193 < 1e-12
clozapine 500 uM 17.4001 < 1e-12
caspofungin 10 nM 16.8296 < 1e-12

More... (click to see all Heterozygous data)

 
Homozygous knockout:

Top 10 sensitivity-inducing conditions for YBR292C Homozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
allyl disulfide 0.06 % 26.5298 < 1e-12
wiskostatin 29 uM 26.1274 < 1e-12
cocl2 1250 uM 10.5813 < 1e-12
sodium sulfate 625 uM 8.75644 1.5587e-10
mpp+ 250 ug/ml 8.65457 2.0582e-10
37 degrees C 0 8.25128 4.9284e-09
synthetic complete for BY4743 0 7.78898 7.435e-06
phosphatase inhibitor 3 uM 7.35622 7.942e-09
zncl2 1875 uM 6.84735 3.4938e-08
ph4 8 6.82623 3.7173e-08

More... (click to see all Homozygous data)





Section 2: Co-fitness interactions.
Gene-gene relationships for YBR292C

Top 10 functional gene interactors with YBR292C. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.



Heterozygous co-fitness interactions

Top 10 interactors with YBR292C by heterozygous co-sensitivity:

Query Interactor Correlation
YBR292C YCR025C 0.87321
YBR292C YCR076C 0.86754
YBR292C DUG2 0.86508
YBR292C YBR284W 0.86272
YBR292C YCR085W 0.85738
YBR292C APE3 0.84822
YBR292C VBA2 0.83985
YBR292C CTP1 0.83897
YBR292C MAL33 0.83575
YBR292C YCR045C 0.83493

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:Component:
  • None
 
Homozygous co-fitness interactions

Top 10 interactors with YBR292C by homozygous co-sensitivity:

Query Interactor Correlation
YBR292C YCR085W 0.83186
YBR292C YBR300C 0.78952
YBR292C PCA1 0.73777
YBR292C YCR049C 0.72887
YBR292C PHO89 0.7256
YBR292C APE3 0.72551
YBR292C YNL203C 0.70837
YBR292C YNL196C 0.69081
YBR292C PMP1 0.68212
YBR292C YDL025C 0.67923

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:
  • None
Component:
  • None




External information about YBR292C

Other databases:

Visit YBR292C in [ SGD | TheBioGrid | BioPixie ]


Previously known GO terms:
    Process:
    • None
    Function:
    • None
    Component:
    • None

Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.


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