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Yeast Fitness

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YBR243C / ALG7

Section 1: Phenotypes.
Gene-drug relationships for YBR243C
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YBR243C deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

Heterozygous knockout:

Top 10 sensitivity-inducing conditions for ALG7 Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
tunicamycin 0.15 uM 17.2872 5.9321e-06
tunicamycin 0.6 uM 10.7353 6.0765e-05
cantharidin 250 uM 9.52086 0.0054263
amphotericin b 0.62 uM 8.28525 4.9567e-11
dyclonine 500 uM 6.94855 7.7089e-06
haloperidol 125 uM 6.86584 6.532e-09
fenpropimorph 2.3 uM 6.72421 1.0716e-08
tunicamycin 0.6 uM 5.83557 1.266e-05
fluconazole 31.25 uM 5.43076 9.6718e-07
haloperidol 250 uM 5.0861 0.00013396

More... (click to see all Heterozygous data)

Homozygous knockout:

[No Homozygous results.]

Section 2: Co-fitness interactions.
Gene-gene relationships for YBR243C

Top 10 functional gene interactors with YBR243C. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.

Heterozygous co-fitness interactions

Top 10 interactors with ALG7 by heterozygous co-sensitivity:

Query Interactor Correlation
ALG7 BOS1 0.49057
ALG7 DCS1 0.47816
ALG7 YGR150C 0.46628
ALG7 NCB2 0.45857
ALG7 RRP1 0.45466
ALG7 MSM1 0.43625
ALG7 TRR1 0.43305
ALG7 GLN4 0.42503
ALG7 SRP101 0.42391
ALG7 GPI17 0.42306

More... (click to see all interactions)

Enriched GO terms of interactors

  • None
  • None
  • None
Homozygous co-fitness interactions

[No homozygous results.]

External information about YBR243C

Other databases:

Visit YBR243C in [ SGD | TheBioGrid | BioPixie ]

Previously known GO terms:
Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.

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