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YBL100C / YBL100C



Section 1: Phenotypes.
Gene-drug relationships for YBL100C
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YBL100C deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

.
Heterozygous knockout:

Top 10 sensitivity-inducing conditions for YBL100C Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
tryptanthrin 250 uM 3.97923 0.00018563
no drug minimal media 0 3.19218 0.012103
atorvastatin 125 uM 3.04501 0.0019029
no drug minimal media 0 3.00093 0.015034
no drug minimal media 0 2.76184 0.019874
no drug minimal media 0 2.62326 0.023456
aminophenazone 250 uM 2.13828 0.018862
resveratrol 2000 uM 2.05688 0.023963
haloperidol 250 uM 2.00415 0.034079
lovastatin 154.5 uM 1.99844 0.025736

More... (click to see all Heterozygous data)

 
Homozygous knockout:

Top 10 sensitivity-inducing conditions for YBL100C Homozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
angelicin 62.5 uM 2.07469 0.026315
methotrexate 500 uM 1.96483 0.032531
bleomycin 1.13 ug/ml 1.69108 0.054031
latrunculin 0.78 uM 1.62591 0.060675
hydroxyurea 50000 uM 1.55059 0.069202
5-fluorouracil 19.2 uM 1.3307 0.10043
psoralen 0.5 uM 1.23505 0.11635
aureobasidin a 0.02 ug/ml 1.21601 0.11984
mms 0.002 % 1.18539 0.12564
licl 100 mM 1.14732 0.13314

More... (click to see all Homozygous data)





Section 2: Co-fitness interactions.
Gene-gene relationships for YBL100C

Top 10 functional gene interactors with YBL100C. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.



Heterozygous co-fitness interactions

Top 10 interactors with YBL100C by heterozygous co-sensitivity:

Query Interactor Correlation
YBL100C MRP7 0.43441
YBL100C YDL163W 0.4284
YBL100C BBP1 0.398
YBL100C GAB1 0.39459
YBL100C YLR202C 0.39441
YBL100C YJR012C 0.38738
YBL100C FAB1 0.38083
YBL100C ATP3 0.38068
YBL100C YFL042C 0.38048
YBL100C SAR1 0.37879

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:Component:
  • None
 
Homozygous co-fitness interactions

[No homozygous results.]




External information about YBL100C

Other databases:

Visit YBL100C in [ SGD | TheBioGrid | BioPixie ]


Previously known GO terms:
    Process:
    • None
    Function:
    • None
    Component:
    • None

Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.


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