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YBL048W / YBL048W



Section 1: Phenotypes.
Gene-drug relationships for YBL048W
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YBL048W deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

.
Heterozygous knockout:

Top 10 sensitivity-inducing conditions for YBL048W Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
cantharidin 250 uM 37.6108 0.00035309
cantharidin 250 uM 15.3573 0.0021066
cantharidin 250 uM 13.5016 0.0027205
psoralen 62.5 uM 4.34801 6.527e-05
lapachol 500 uM 3.79141 0.00021326
nocodazole 2 ug/ml 2.58293 0.0064848
chlorambucil 1000 uM 2.47937 0.0084022
sodium fluoride 10000 uM 2.37907 0.011745
cantharidin 250 uM 2.3749 0.0704
Tyrphostin 6.2 uM 2.34278 0.012761

More... (click to see all Heterozygous data)

 
Homozygous knockout:

Top 10 sensitivity-inducing conditions for YBL048W Homozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
wiskostatin 29 uM 6.22189 2.2216e-07
carboplatin 700 uM 4.97594 4.8903e-05
licl 100 mM 4.21198 0.00026204
mitomycin c 1000 uM 4.02159 0.00022095
sodium fluoride 20000 uM 3.98723 0.00016794
angelicin 62.5 uM 3.90855 0.00051481
synthetic complete for BY4743 0 3.832 0.001654
synthetic complete for BY4743 400 uM 3.45113 0.0015253
lysine dropout 0 3.22824 0.002469
cisplatin 31.25 uM 3.05745 0.0025585

More... (click to see all Homozygous data)





Section 2: Co-fitness interactions.
Gene-gene relationships for YBL048W

Top 10 functional gene interactors with YBL048W. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.



Heterozygous co-fitness interactions

Top 10 interactors with YBL048W by heterozygous co-sensitivity:

Query Interactor Correlation
YBL048W SOL4 0.73373
YBL048W TPC1 0.70898
YBL048W PXA2 0.70877
YBL048W SVS1 0.70856
YBL048W YNL155W 0.70793
YBL048W YOR263C 0.70669
YBL048W YOL046C 0.70605
YBL048W YMR041C 0.70355
YBL048W PPR1 0.70112
YBL048W DUR3 0.69917

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:
  • None
Component:
  • None
 
Homozygous co-fitness interactions

Top 10 interactors with YBL048W by homozygous co-sensitivity:

Query Interactor Correlation
YBL048W AST1 0.6981
YBL048W KNH1 0.65057
YBL048W PDR3 0.62698
YBL048W YBL029W 0.62127
YBL048W ADH7 0.61971
YBL048W ATO2 0.61231
YBL048W FRE2 0.61223
YBL048W YBL028C 0.59919
YBL048W YMR147W 0.59585
YBL048W YCL075W 0.59406

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:
  • None
Component:
  • None




External information about YBL048W

Other databases:

Visit YBL048W in [ SGD | TheBioGrid | BioPixie ]


Previously known GO terms:
    Process:
    • None
    Function:
    • None
    Component:
    • None

Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.


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