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Yeast Fitness
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YBL013W / FMT1



Section 1: Phenotypes.
Gene-drug relationships for YBL013W
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YBL013W deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

.
Heterozygous knockout:

Top 10 sensitivity-inducing conditions for FMT1 Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
alverine citrate 500 uM 15.3349 1.5092e-09
wiskostatin 29 uM 13.9465 < 1e-12
clozapine 500 uM 11.8116 < 1e-12
drofenine hydrochloride 750 uM 11.6515 < 1e-12
nocodazole 2 ug/ml 10.3936 < 1e-12
miconazole 0.2 uM 9.62226 2.3405e-08
mitomycin c 1000 uM 9.08346 4.8661e-12
no drug minimal media 0 8.88829 0.00014997
caspofungin 10 nM 8.68702 1.3882e-11
ketoconazole 11.8 uM 8.63353 1.0176e-07

More... (click to see all Heterozygous data)

 
Homozygous knockout:

Top 10 sensitivity-inducing conditions for FMT1 Homozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
synthetic complete for BY4743 0 34.5036 1.9233e-07
synthetic complete for BY4743 0 27.671 5.7689e-07
23 degrees C 0 22.2293 3.8099e-10
synthetic complete for BY4743 0 11.1533 5.0532e-05
synthetic complete for BY4743 0 7.438 0.00087236
synthetic complete for BY4743 0 6.80673 0.0012171
tryptophan dropout 0 4.66874 0.00044125
synthetic complete for BY4743 0 4.42374 0.0006433
synthetic complete for BY4743 0 4.01479 0.0012295
synthetic complete for BY4743 0 4.01036 0.002561

More... (click to see all Homozygous data)





Section 2: Co-fitness interactions.
Gene-gene relationships for YBL013W

Top 10 functional gene interactors with YBL013W. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.



Heterozygous co-fitness interactions

Top 10 interactors with FMT1 by heterozygous co-sensitivity:

Query Interactor Correlation
FMT1 LSM2 0.44504
FMT1 HSV2 0.42633
FMT1 GFD2 0.39523
FMT1 RPL32 0.3926
FMT1 MRS5 0.38305
FMT1 SLI15 0.37132
FMT1 YGR205W 0.3653
FMT1 VPS1 0.3612
FMT1 MTR4 0.3529
FMT1 SDO1 0.35199

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:
  • None
Component:
  • None
 
Homozygous co-fitness interactions

Top 10 interactors with FMT1 by homozygous co-sensitivity:

Query Interactor Correlation
FMT1 YLR218C 0.56864
FMT1 YEL028W 0.50222
FMT1 YLR124W 0.4983
FMT1 PRM2 0.45097
FMT1 YBL029W 0.44274
FMT1 ARO10 0.44239
FMT1 TDP1 0.43742
FMT1 YER039C-A 0.43599
FMT1 YKR017C 0.43461
FMT1 LSB5 0.42996

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:
  • None
Component:
  • None




External information about YBL013W

Other databases:

Visit YBL013W in [ SGD | TheBioGrid | BioPixie ]


Previously known GO terms:
Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.


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