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YAL061W / YAL061W



Section 1: Phenotypes.
Gene-drug relationships for YAL061W
(Hillenmeyer et al., Science 2008)

The top 10 experiments that caused a fitness defect in the YAL061W deletion mutants. On the left is a table listing the top 10 conditions inducing sensitivity; on the right is a visualization of those conditions. Edges may appear more than once if the condition was tested multiple times.

We generally recommend using a significance cutoff of p-value < 0.01. For the "phenotype for all genes" analysis, we used p-value < 1e-5 to control for multiple hypothesis testing. For details, see
The Chemical Genomic Portrait of Yeast.

.
Heterozygous knockout:

Top 10 sensitivity-inducing conditions for YAL061W Heterozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
progesterone 250 uM 6.80156 8.1772e-09
bithionol 75 uM 6.26666 5.3075e-08
mechlorethamine 500 uM 4.68829 1.1965e-05
methotrexate 500 uM 3.9606 0.00019559
cantharidin 250 uM 3.93239 0.029501
dyclonine 500 uM 3.189 0.003895
cuso4 10000 uM 2.62051 0.0066593
fenpropimorph 2.3 uM 2.45184 0.015245
tunicamycin 0.15 uM 2.43691 0.013433
miconazole 50 nM 2.11375 0.025296

More... (click to see all Heterozygous data)

 
Homozygous knockout:

Top 10 sensitivity-inducing conditions for YAL061W Homozygous deletion:

Condition1 Conc Unit z_result_nm z_tdist_pval_nm
mms 0.002 % 7.66245 2.2516e-07
nocodazole 10 ug/ml 4.65766 9.7905e-05
clotrimazole 2 uM 3.71408 0.00049048
mechlorethamine 62.5 uM 3.2236 0.042124
cantharidin analog 250 ug/ml 3.22149 0.0014043
lovastatin 154.5 uM 2.90942 0.0036623
nitric oxide 800 uM 2.69577 0.006075
latrunculin 3 uM 2.38119 0.014252
ID 652287 500 uM 2.15903 0.018997
ID 632839 62.5 uM 2.15854 0.019017

More... (click to see all Homozygous data)





Section 2: Co-fitness interactions.
Gene-gene relationships for YAL061W

Top 10 functional gene interactors with YAL061W. These relationships were calculated using the Pearson correlation of each gene's scores across drug experiments.



Heterozygous co-fitness interactions

Top 10 interactors with YAL061W by heterozygous co-sensitivity:

Query Interactor Correlation
YAL061W UIP3 0.67803
YAL061W GDH3 0.60054
YAL061W YAR030C 0.59698
YAL061W SNC1 0.59266
YAL061W BDH1 0.59196
YAL061W OAF1 0.59002
YAL061W PAU8 0.57438
YAL061W SUB1 0.57105
YAL061W FMS1 0.54645
YAL061W STB4 0.54223

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:
  • None
Component:
  • None
 
Homozygous co-fitness interactions

Top 10 interactors with YAL061W by homozygous co-sensitivity:

Query Interactor Correlation
YAL061W YCL023C 0.75633
YAL061W GDH3 0.72647
YAL061W YAL045C 0.72083
YAL061W YKL161C 0.71852
YAL061W YJR100C 0.7104
YAL061W MAL12 0.70324
YAL061W YTA6 0.70279
YAL061W YJR098C 0.70129
YAL061W TOS2 0.69629
YAL061W ADE16 0.69426

More... (click to see all interactions)

Enriched GO terms of interactors

Process:
  • None
Function:Component:
  • None




External information about YAL061W

Other databases:

Visit YAL061W in [ SGD | TheBioGrid | BioPixie ]


Previously known GO terms:
Visualizations of other datasets

Co-expression, physical interaction, synthetic lethality. Can post if requested by users.


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